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MDM2 regulates dihydrofolate reductase activity through monoubiquitination.

Maguire M, Nield PC, Devling T, Jenkins RE, Park BK, Polański R, Vlatković N, Boyd MT. Maguire M, et al. Among authors: nield pc. Cancer Res. 2008 May 1;68(9):3232-42. doi: 10.1158/0008-5472.CAN-07-5271. Cancer Res. 2008. PMID: 18451149 Free PMC article.

MDM2 interacts with NME2 (non-metastatic cells 2, protein) and suppresses the ability of NME2 to negatively regulate cell motility.

Polanski R, Maguire M, Nield PC, Jenkins RE, Park BK, Krawczynska K, Devling T, Ray-Sinha A, Rubbi CP, Vlatkovic N, Boyd MT. Polanski R, et al. Among authors: nield pc. Carcinogenesis. 2011 Aug;32(8):1133-42. doi: 10.1093/carcin/bgr070. Epub 2011 Apr 18. Carcinogenesis. 2011. PMID: 21504894

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