Vanhaesebroeck B - Search Results

1

Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma.

Krishnamoorthy N, Oriss TB, Paglia M, Fei M, Yarlagadda M, Vanhaesebroeck B, Ray A, Ray P. Krishnamoorthy N, et al. Among authors: vanhaesebroeck b. Nat Med. 2008 May;14(5):565-73. doi: 10.1038/nm1766. Epub 2008 May 4. Nat Med. 2008. PMID: 18454155 Free PMC article.

2

PI3K in lymphocyte development, differentiation and activation.

Okkenhaug K, Vanhaesebroeck B. Okkenhaug K, et al. Among authors: vanhaesebroeck b. Nat Rev Immunol. 2003 Apr;3(4):317-30. doi: 10.1038/nri1056. Nat Rev Immunol. 2003. PMID: 12669022 Review.

3

Essential role for the p110delta phosphoinositide 3-kinase in the allergic response.

Ali K, Bilancio A, Thomas M, Pearce W, Gilfillan AM, Tkaczyk C, Kuehn N, Gray A, Giddings J, Peskett E, Fox R, Bruce I, Walker C, Sawyer C, Okkenhaug K, Finan P, Vanhaesebroeck B. Ali K, et al. Among authors: vanhaesebroeck b. Nature. 2004 Oct 21;431(7011):1007-11. doi: 10.1038/nature02991. Nature. 2004. PMID: 15496927 Free article.

4

Role of the phosphoinositide 3-kinase p110delta in generation of type 2 cytokine responses and allergic airway inflammation.

Nashed BF, Zhang T, Al-Alwan M, Srinivasan G, Halayko AJ, Okkenhaug K, Vanhaesebroeck B, Hayglass KT, Marshall AJ. Nashed BF, et al. Among authors: vanhaesebroeck b. Eur J Immunol. 2007 Feb;37(2):416-24. doi: 10.1002/eji.200636401. Eur J Immunol. 2007. PMID: 17236236 Free article.

5

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.

Graupera M, Guillermet-Guibert J, Foukas LC, Phng LK, Cain RJ, Salpekar A, Pearce W, Meek S, Millan J, Cutillas PR, Smith AJ, Ridley AJ, Ruhrberg C, Gerhardt H, Vanhaesebroeck B. Graupera M, et al. Among authors: vanhaesebroeck b. Nature. 2008 May 29;453(7195):662-6. doi: 10.1038/nature06892. Epub 2008 Apr 30. Nature. 2008. PMID: 18449193

6

Btk-dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cells.

Kuehn HS, Rådinger M, Brown JM, Ali K, Vanhaesebroeck B, Beaven MA, Metcalfe DD, Gilfillan AM. Kuehn HS, et al. Among authors: vanhaesebroeck b. J Cell Sci. 2010 Aug 1;123(Pt 15):2576-85. doi: 10.1242/jcs.071043. Epub 2010 Jun 29. J Cell Sci. 2010. PMID: 20587594 Free PMC article.

7

Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.

Ali K, Soond DR, Pineiro R, Hagemann T, Pearce W, Lim EL, Bouabe H, Scudamore CL, Hancox T, Maecker H, Friedman L, Turner M, Okkenhaug K, Vanhaesebroeck B. Ali K, et al. Among authors: vanhaesebroeck b. Nature. 2014 Jun 19;510(7505):407-411. doi: 10.1038/nature13444. Epub 2014 Jun 11. Nature. 2014. PMID: 24919154 Free PMC article.

8

Phosphatidylinositol-3-OH kinase as a direct target of Ras.

Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J. Rodriguez-Viciana P, et al. Among authors: vanhaesebroeck b. Nature. 1994 Aug 18;370(6490):527-32. doi: 10.1038/370527a0. Nature. 1994. PMID: 8052307

9

Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells.

Wen PJ, Osborne SL, Zanin M, Low PC, Wang HT, Schoenwaelder SM, Jackson SP, Wedlich-Söldner R, Vanhaesebroeck B, Keating DJ, Meunier FA. Wen PJ, et al. Among authors: vanhaesebroeck b. Nat Commun. 2011 Oct 4;2:491. doi: 10.1038/ncomms1500. Nat Commun. 2011. PMID: 21971506 Free article.

10

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.

Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno IM, Nock G, Filloux A, Beyaert R, Flamand V, Vanhaesebroeck B. Aksoy E, et al. Among authors: vanhaesebroeck b. Nat Immunol. 2012 Nov;13(11):1045-1054. doi: 10.1038/ni.2426. Epub 2012 Sep 30. Nat Immunol. 2012. PMID: 23023391 Free PMC article.

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