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Passive oral drug absorption can be predicted more reliably by experimental than computational models--fact or myth.
Eur J Pharm Sci. 2008 Jul 3;34(2-3):129-39. doi: 10.1016/j.ejps.2008.03.001. Epub 2008 Mar 15.
Eur J Pharm Sci. 2008.
PMID: 18455374
Computational prediction of oral drug absorption based on absorption rate constants in humans.
Linnankoski J, Mäkelä JM, Ranta VP, Urtti A, Yliperttula M.
Linnankoski J, et al.
J Med Chem. 2006 Jun 15;49(12):3674-81. doi: 10.1021/jm051231p.
J Med Chem. 2006.
PMID: 16759110
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Paracellular porosity and pore size of the human intestinal epithelium in tissue and cell culture models.
Linnankoski J, Mäkelä J, Palmgren J, Mauriala T, Vedin C, Ungell AL, Lazorova L, Artursson P, Urtti A, Yliperttula M.
Linnankoski J, et al.
J Pharm Sci. 2010 Apr;99(4):2166-75. doi: 10.1002/jps.21961.
J Pharm Sci. 2010.
PMID: 19827099
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