van Staden C - Search Results

1

Development of a homogeneous high-throughput live-cell G-protein-coupled receptor binding assay.

Lee PH, Miller SC, van Staden C, Cromwell EF. Lee PH, et al. Among authors: van staden c. J Biomol Screen. 2008 Sep;13(8):748-54. doi: 10.1177/1087057108317835. Epub 2008 May 6. J Biomol Screen. 2008. PMID: 18460694

2

Enhanced selectivity screening of GPCR ligands using a label-free cell based assay technology.

McGuinness RP, Proctor JM, Gallant DL, van Staden CJ, Ly JT, Tang FL, Lee PH. McGuinness RP, et al. Among authors: van staden cj. Comb Chem High Throughput Screen. 2009 Sep;12(8):812-23. doi: 10.2174/138620709789104861. Epub 2009 Sep 1. Comb Chem High Throughput Screen. 2009. PMID: 19531008

3

Evaluation of dynamic mass redistribution technology for pharmacological studies of recombinant and endogenously expressed g protein-coupled receptors.

Lee PH, Gao A, van Staden C, Ly J, Salon J, Xu A, Fang Y, Verkleeren R. Lee PH, et al. Among authors: van staden c. Assay Drug Dev Technol. 2008 Feb;6(1):83-94. doi: 10.1089/adt.2007.126. Assay Drug Dev Technol. 2008. PMID: 18336088

4

Membrane vesicle ABC transporter assays for drug safety assessment.

van Staden CJ, Morgan RE, Ramachandran B, Chen Y, Lee PH, Hamadeh HK. van Staden CJ, et al. Curr Protoc Toxicol. 2012 Nov;Chapter 23:Unit 23.5. doi: 10.1002/0471140856.tx2305s54. Curr Protoc Toxicol. 2012. PMID: 23169270

5

Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

Morgan RE, Trauner M, van Staden CJ, Lee PH, Ramachandran B, Eschenberg M, Afshari CA, Qualls CW Jr, Lightfoot-Dunn R, Hamadeh HK. Morgan RE, et al. Toxicol Sci. 2010 Dec;118(2):485-500. doi: 10.1093/toxsci/kfq269. Epub 2010 Sep 9. Toxicol Sci. 2010. PMID: 20829430

6

Agonists of the orphan human G2A receptor identified from inducible G2A expression and beta-lactamase reporter screen.

Bercher M, Hanson B, van Staden C, Wu K, Ng GY, Lee PH. Bercher M, et al. Among authors: van staden c. Assay Drug Dev Technol. 2009 Apr;7(2):133-42. doi: 10.1089/adt.2008.179. Assay Drug Dev Technol. 2009. PMID: 19505230

7

Development of multiplexed microarray binding assays for high-throughput drug discovery.

Hong Y, Liu L, Pai S, Graf JN, Rao H, Lynn JG, van Staden C, Lee PH, Lai F, Salon JA. Hong Y, et al. Among authors: van staden c. Assay Drug Dev Technol. 2009 Jun;7(3):281-93. doi: 10.1089/adt.2008.180. Assay Drug Dev Technol. 2009. PMID: 19604106

8

Solid-phase synthesis and structure-activity relationships of novel biarylethers as melanin-concentrating hormone receptor-1 antagonists.

Ma V, Bannon AW, Baumgartner J, Hale C, Hsieh F, Hulme C, Rorrer K, Salon J, van Staden C, Tempest P. Ma V, et al. Among authors: van staden c. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5066-72. doi: 10.1016/j.bmcl.2006.07.040. Epub 2006 Aug 1. Bioorg Med Chem Lett. 2006. PMID: 16887348

9

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Morgan RE, van Staden CJ, Chen Y, Kalyanaraman N, Kalanzi J, Dunn RT 2nd, Afshari CA, Hamadeh HK. Morgan RE, et al. Among authors: van staden cj. Toxicol Sci. 2013 Nov;136(1):216-41. doi: 10.1093/toxsci/kft176. Epub 2013 Aug 16. Toxicol Sci. 2013. PMID: 23956101

10

Posttraumatic anxiety-like behaviour in zebrafish is dose-dependently attenuated by the alpha-2A receptor agonist, guanfacine.

van Staden C, Weinshenker D, Finger-Baier K, Botha TL, Brand L, Wolmarans W. van Staden C, et al. Behav Pharmacol. 2025 Feb 1;36(1):47-59. doi: 10.1097/FBP.0000000000000808. Epub 2024 Dec 24. Behav Pharmacol. 2025. PMID: 39718044

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