Willis CL - Search Results

1

In vivo mutational analysis of the mupirocin gene cluster reveals labile points in the biosynthetic pathway: the "leaky hosepipe" mechanism.

Wu J, Hothersall J, Mazzetti C, O'Connell Y, Shields JA, Rahman AS, Cox RJ, Crosby J, Simpson TJ, Thomas CM, Willis CL. Wu J, et al. Among authors: willis cl. Chembiochem. 2008 Jun 16;9(9):1500-8. doi: 10.1002/cbic.200800085. Chembiochem. 2008. PMID: 18465759

2

Synthesis and incorporation of the first polyketide synthase free intermediate in monocerin biosynthesis.

Axford LC, Simpson TJ, Willis CL. Axford LC, et al. Among authors: willis cl. Angew Chem Int Ed Engl. 2004 Jan 30;43(6):727-30. doi: 10.1002/anie.200352652. Angew Chem Int Ed Engl. 2004. PMID: 14755704 No abstract available.

3

Assembly intermediates in polyketide biosynthesis: enantioselective syntheses of beta-hydroxycarbonyl compounds.

Le Sann C, Munoz DM, Saunders N, Simpson TJ, Smith DI, Soulas F, Watts P, Willis CL. Le Sann C, et al. Among authors: willis cl. Org Biomol Chem. 2005 May 7;3(9):1719-28. doi: 10.1039/b419492f. Epub 2005 Mar 31. Org Biomol Chem. 2005. PMID: 15858656

4

Synthesis of [1,2-13C2, 15N]-L-homoserine and its incorporation by the PKS-NRPS system of Fusarium moniliforme into the mycotoxin fusarin C.

Rees DO, Bushby N, Cox RJ, Harding JR, Simpson TJ, Willis CL. Rees DO, et al. Among authors: willis cl. Chembiochem. 2007 Jan 2;8(1):46-50. doi: 10.1002/cbic.200600404. Chembiochem. 2007. PMID: 17121404 No abstract available.

5

Mutational analysis reveals that all tailoring region genes are required for production of polyketide antibiotic mupirocin by pseudomonas fluorescens: pseudomonic acid B biosynthesis precedes pseudomonic acid A.

Hothersall J, Wu J, Rahman AS, Shields JA, Haddock J, Johnson N, Cooper SM, Stephens ER, Cox RJ, Crosby J, Willis CL, Simpson TJ, Thomas CM. Hothersall J, et al. Among authors: willis cl. J Biol Chem. 2007 May 25;282(21):15451-61. doi: 10.1074/jbc.M701490200. Epub 2007 Mar 23. J Biol Chem. 2007. PMID: 17383964 Free article.

6

Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens.

Wu J, Cooper SM, Cox RJ, Crosby J, Crump MP, Hothersall J, Simpson TJ, Thomas CM, Willis CL. Wu J, et al. Among authors: willis cl. Chem Commun (Camb). 2007 May 28;(20):2040-2. doi: 10.1039/b700613f. Chem Commun (Camb). 2007. PMID: 17713071

7

Probing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2).

Evans SE, Williams C, Arthur CJ, Płoskoń E, Wattana-amorn P, Cox RJ, Crosby J, Willis CL, Simpson TJ, Crump MP. Evans SE, et al. Among authors: willis cl. J Mol Biol. 2009 Jun 12;389(3):511-28. doi: 10.1016/j.jmb.2009.03.072. Epub 2009 Apr 8. J Mol Biol. 2009. PMID: 19361520

8

Resistance to and synthesis of the antibiotic mupirocin.

Thomas CM, Hothersall J, Willis CL, Simpson TJ. Thomas CM, et al. Among authors: willis cl. Nat Rev Microbiol. 2010 Apr;8(4):281-9. doi: 10.1038/nrmicro2278. Epub 2010 Mar 1. Nat Rev Microbiol. 2010. PMID: 20190824 Review.

9

Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis.

Płoskoń E, Arthur CJ, Kanari AL, Wattana-amorn P, Williams C, Crosby J, Simpson TJ, Willis CL, Crump MP. Płoskoń E, et al. Among authors: willis cl. Chem Biol. 2010 Jul 30;17(7):776-85. doi: 10.1016/j.chembiol.2010.05.024. Chem Biol. 2010. PMID: 20659690

10

Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production.

Hothersall J, Murphy AC, Iqbal Z, Campbell G, Stephens ER, Wu J, Cooper H, Atkinson S, Williams P, Crosby J, Willis CL, Cox RJ, Simpson TJ, Thomas CM. Hothersall J, et al. Among authors: willis cl. Appl Microbiol Biotechnol. 2011 May;90(3):1017-26. doi: 10.1007/s00253-011-3145-2. Epub 2011 Feb 12. Appl Microbiol Biotechnol. 2011. PMID: 21318358

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