Mu J - Search Results

1

Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states.

Muise ES, Azzolina B, Kuo DW, El-Sherbeini M, Tan Y, Yuan X, Mu J, Thompson JR, Berger JP, Wong KK. Muise ES, et al. Among authors: mu j. Mol Pharmacol. 2008 Aug;74(2):403-12. doi: 10.1124/mol.108.044826. Epub 2008 May 8. Mol Pharmacol. 2008. PMID: 18467542

2

FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents.

Mu J, Pinkstaff J, Li Z, Skidmore L, Li N, Myler H, Dallas-Yang Q, Putnam AM, Yao J, Bussell S, Wu M, Norman TC, Rodriguez CG, Kimmel B, Metzger JM, Manibusan A, Lee D, Zaller DM, Zhang BB, DiMarchi RD, Berger JP, Axelrod DW. Mu J, et al. Diabetes. 2012 Feb;61(2):505-12. doi: 10.2337/db11-0838. Epub 2011 Dec 30. Diabetes. 2012. PMID: 22210323 Free PMC article.

3

Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist.

Mu J, Qureshi SA, Brady EJ, Muise ES, Candelore MR, Jiang G, Li Z, Wu MS, Yang X, Dallas-Yang Q, Miller C, Xiong Y, Langdon RB, Parmee ER, Zhang BB. Mu J, et al. PLoS One. 2012;7(11):e49572. doi: 10.1371/journal.pone.0049572. Epub 2012 Nov 19. PLoS One. 2012. PMID: 23185367 Free PMC article.

4

Downstream signaling pathways in mouse adipose tissues following acute in vivo administration of fibroblast growth factor 21.

Muise ES, Souza S, Chi A, Tan Y, Zhao X, Liu F, Dallas-Yang Q, Wu M, Sarr T, Zhu L, Guo H, Li Z, Li W, Hu W, Jiang G, Paweletz CP, Hendrickson RC, Thompson JR, Mu J, Berger JP, Mehmet H. Muise ES, et al. Among authors: mu j. PLoS One. 2013 Sep 6;8(9):e73011. doi: 10.1371/journal.pone.0073011. eCollection 2013. PLoS One. 2013. PMID: 24039848 Free PMC article.

5

Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia.

Conarello SL, Jiang G, Mu J, Li Z, Woods J, Zycband E, Ronan J, Liu F, Roy RS, Zhu L, Charron MJ, Zhang BB. Conarello SL, et al. Among authors: mu j. Diabetologia. 2007 Jan;50(1):142-50. doi: 10.1007/s00125-006-0481-3. Epub 2006 Nov 28. Diabetologia. 2007. PMID: 17131145

6

Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes.

Mu J, Petrov A, Eiermann GJ, Woods J, Zhou YP, Li Z, Zycband E, Feng Y, Zhu L, Roy RS, Howard AD, Li C, Thornberry NA, Zhang BB. Mu J, et al. Eur J Pharmacol. 2009 Nov 25;623(1-3):148-54. doi: 10.1016/j.ejphar.2009.09.027. Epub 2009 Sep 16. Eur J Pharmacol. 2009. PMID: 19765579

7

Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.

Mu J, Woods J, Zhou YP, Roy RS, Li Z, Zycband E, Feng Y, Zhu L, Li C, Howard AD, Moller DE, Thornberry NA, Zhang BB. Mu J, et al. Diabetes. 2006 Jun;55(6):1695-704. doi: 10.2337/db05-1602. Diabetes. 2006. PMID: 16731832

8

The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin.

Kosinski JR, Hubert J, Carrington PE, Chicchi GG, Mu J, Miller C, Cao J, Bianchi E, Pessi A, Sinharoy R, Marsh DJ, Pocai A. Kosinski JR, et al. Among authors: mu j. Obesity (Silver Spring). 2012 Aug;20(8):1566-71. doi: 10.1038/oby.2012.67. Epub 2012 Mar 16. Obesity (Silver Spring). 2012. PMID: 22421924 Free PMC article.

9

Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.

Wu M, Carballo-Jane E, Zhou H, Zafian P, Dai G, Liu M, Lao J, Kelly T, Shao D, Gorski J, Pissarnitski D, Kekec A, Chen Y, Previs SF, Scapin G, Gomez-Llorente Y, Hollingsworth SA, Yan L, Feng D, Huo P, Walford G, Erion MD, Kelley DE, Lin S, Mu J. Wu M, et al. Among authors: mu j. Nat Commun. 2022 Feb 17;13(1):942. doi: 10.1038/s41467-022-28561-9. Nat Commun. 2022. PMID: 35177603 Free PMC article.

10

Potentiation of insulin-mediated glucose lowering without elevated hypoglycemia risk by a small molecule insulin receptor modulator.

Wu M, Dai G, Yao J, Hoyt S, Wang L, Mu J. Wu M, et al. Among authors: mu j. PLoS One. 2015 Mar 23;10(3):e0122012. doi: 10.1371/journal.pone.0122012. eCollection 2015. PLoS One. 2015. PMID: 25799496 Free PMC article.

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