Takimoto E - Search Results

1

Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy.

Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, Ketner EA, Majmudar M, Gabrielson K, Halushka MK, Mitchell JB, Biswal S, Channon KM, Wolin MS, Alp NJ, Paolocci N, Champion HC, Kass DA. Moens AL, et al. Among authors: takimoto e. Circulation. 2008 May 20;117(20):2626-36. doi: 10.1161/CIRCULATIONAHA.107.737031. Epub 2008 May 12. Circulation. 2008. PMID: 18474817 Free PMC article.

2

Calcineurin plays a critical role in pressure overload-induced cardiac hypertrophy.

Shimoyama M, Hayashi D, Takimoto E, Zou Y, Oka T, Uozumi H, Kudoh S, Shibasaki F, Yazaki Y, Nagai R, Komuro I. Shimoyama M, et al. Among authors: takimoto e. Circulation. 1999 Dec 14;100(24):2449-54. doi: 10.1161/01.cir.100.24.2449. Circulation. 1999. PMID: 10595959

3

Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension.

Shimoyama M, Hayashi D, Zou Y, Takimoto E, Mizukami M, Monzen K, Kudoh S, Hiroi Y, Yazaki Y, Nagai R, Komuro I. Shimoyama M, et al. Among authors: takimoto e. Circulation. 2000 Oct 17;102(16):1996-2004. doi: 10.1161/01.cir.102.16.1996. Circulation. 2000. PMID: 11034951

4

Calcineurin plays a critical role in the development of pressure overload-induced cardiac hypertrophy.

Zou Y, Hiroi Y, Uozumi H, Takimoto E, Toko H, Zhu W, Kudoh S, Mizukami M, Shimoyama M, Shibasaki F, Nagai R, Yazaki Y, Komuro I. Zou Y, et al. Among authors: takimoto e. Circulation. 2001 Jul 3;104(1):97-101. doi: 10.1161/01.cir.104.1.97. Circulation. 2001. PMID: 11435345

5

Frequency- and afterload-dependent cardiac modulation in vivo by troponin I with constitutively active protein kinase A phosphorylation sites.

Takimoto E, Soergel DG, Janssen PM, Stull LB, Kass DA, Murphy AM. Takimoto E, et al. Circ Res. 2004 Mar 5;94(4):496-504. doi: 10.1161/01.RES.0000117307.57798.F5. Epub 2004 Jan 15. Circ Res. 2004. PMID: 14726477

6

Modulation of in vivo cardiac function by myocyte-specific nitric oxide synthase-3.

Champion HC, Georgakopoulos D, Takimoto E, Isoda T, Wang Y, Kass DA. Champion HC, et al. Among authors: takimoto e. Circ Res. 2004 Mar 19;94(5):657-63. doi: 10.1161/01.RES.0000119323.79644.20. Epub 2004 Jan 29. Circ Res. 2004. PMID: 14752030

7

cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.

Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA. Takimoto E, et al. Circ Res. 2005 Jan 7;96(1):100-9. doi: 10.1161/01.RES.0000152262.22968.72. Epub 2004 Dec 2. Circ Res. 2005. PMID: 15576651

8

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.

Takimoto E, Champion HC, Li M, Belardi D, Ren S, Rodriguez ER, Bedja D, Gabrielson KL, Wang Y, Kass DA. Takimoto E, et al. Nat Med. 2005 Feb;11(2):214-22. doi: 10.1038/nm1175. Epub 2005 Jan 23. Nat Med. 2005. PMID: 15665834

9

Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism.

Champion HC, Bivalacqua TJ, Takimoto E, Kass DA, Burnett AL. Champion HC, et al. Among authors: takimoto e. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1661-6. doi: 10.1073/pnas.0407183102. Epub 2005 Jan 24. Proc Natl Acad Sci U S A. 2005. PMID: 15668387 Free PMC article.

10

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load.

Takimoto E, Champion HC, Li M, Ren S, Rodriguez ER, Tavazzi B, Lazzarino G, Paolocci N, Gabrielson KL, Wang Y, Kass DA. Takimoto E, et al. J Clin Invest. 2005 May;115(5):1221-31. doi: 10.1172/JCI21968. Epub 2005 Apr 14. J Clin Invest. 2005. PMID: 15841206 Free PMC article.

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