Markova B - Search Results

1

LS104, a non-ATP-competitive small-molecule inhibitor of JAK2, is potently inducing apoptosis in JAK2V617F-positive cells.

Lipka DB, Hoffmann LS, Heidel F, Markova B, Blum MC, Breitenbuecher F, Kasper S, Kindler T, Levine RL, Huber C, Fischer T. Lipka DB, et al. Among authors: markova b. Mol Cancer Ther. 2008 May;7(5):1176-84. doi: 10.1158/1535-7163.MCT-07-2215. Mol Cancer Ther. 2008. PMID: 18483305

2

The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia.

Kasper S, Breitenbuecher F, Hoehn Y, Heidel F, Lipka DB, Markova B, Huber C, Kindler T, Fischer T. Kasper S, et al. Among authors: markova b. Leuk Res. 2008 Nov;32(11):1698-708. doi: 10.1016/j.leukres.2008.05.003. Epub 2008 Jun 16. Leuk Res. 2008. PMID: 18556063

3

A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML.

Breitenbuecher F, Markova B, Kasper S, Carius B, Stauder T, Böhmer FD, Masson K, Rönnstrand L, Huber C, Kindler T, Fischer T. Breitenbuecher F, et al. Among authors: markova b. Blood. 2009 Apr 23;113(17):4063-73. doi: 10.1182/blood-2007-11-126664. Epub 2009 Jan 14. Blood. 2009. PMID: 19144992 Free article.

4

Pharmacologic inhibition of mTOR antagonizes the cytotoxic activity of pemetrexed in non-small cell lung cancer.

Markova B, Hähnel PS, Kasper S, Herbertz S, Schuler M, Breitenbuecher F. Markova B, et al. J Cancer Res Clin Oncol. 2012 Apr;138(4):545-54. doi: 10.1007/s00432-011-1123-9. Epub 2011 Dec 28. J Cancer Res Clin Oncol. 2012. PMID: 22203472

5

Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor.

Breitenbuecher F, Schnittger S, Grundler R, Markova B, Carius B, Brecht A, Duyster J, Haferlach T, Huber C, Fischer T. Breitenbuecher F, et al. Among authors: markova b. Blood. 2009 Apr 23;113(17):4074-7. doi: 10.1182/blood-2007-11-125476. Epub 2008 May 15. Blood. 2009. PMID: 18483393 Free article.

6

Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway.

Markova B, Albers C, Breitenbuecher F, Melo JV, Brümmendorf TH, Heidel F, Lipka D, Duyster J, Huber C, Fischer T. Markova B, et al. Oncogene. 2010 Feb 4;29(5):739-51. doi: 10.1038/onc.2009.374. Epub 2009 Nov 2. Oncogene. 2010. PMID: 19881535

7

Functional and clinical characterization of the putative tumor suppressor WWOX in non-small cell lung cancer.

Becker S, Markova B, Wiewrodt R, Hoffarth S, Hähnel PS, Pleiner S, Schmidt LH, Breitenbuecher F, Schuler M. Becker S, et al. Among authors: markova b. J Thorac Oncol. 2011 Dec;6(12):1976-83. doi: 10.1097/JTO.0b013e31822e59dd. J Thorac Oncol. 2011. PMID: 21892104 Free article.

8

Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapies.

Kasper S, Breitenbuecher F, Heidel F, Hoffarth S, Markova B, Schuler M, Fischer T. Kasper S, et al. Among authors: markova b. Blood Cancer J. 2012 Mar;2(3):e60. doi: 10.1038/bcj.2012.5. Epub 2012 Mar 9. Blood Cancer J. 2012. PMID: 22829255 Free PMC article.

9

Identification of protein tyrosine phosphatases associating with the PDGF receptor.

Markova B, Herrlich P, Rönnstrand L, Böhmer FD. Markova B, et al. Biochemistry. 2003 Mar 11;42(9):2691-9. doi: 10.1021/bi0265574. Biochemistry. 2003. PMID: 12614164

10

Investigation of protein-tyrosine phosphatases by in-gel assays.

Markova B, Gulati P, Herrlich PA, Böhmer FD. Markova B, et al. Methods. 2005 Jan;35(1):22-7. doi: 10.1016/j.ymeth.2004.07.004. Methods. 2005. PMID: 15588982

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