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Page 1
Mechanisms of chemoresistance to alkylating agents in malignant glioma.
Sarkaria JN, Kitange GJ, James CD, Plummer R, Calvert H, Weller M, Wick W. Sarkaria JN, et al. Among authors: calvert h. Clin Cancer Res. 2008 May 15;14(10):2900-8. doi: 10.1158/1078-0432.CCR-07-1719. Clin Cancer Res. 2008. PMID: 18483356 Free PMC article. Review.
Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors.
Plummer R, Jones C, Middleton M, Wilson R, Evans J, Olsen A, Curtin N, Boddy A, McHugh P, Newell D, Harris A, Johnson P, Steinfeldt H, Dewji R, Wang D, Robson L, Calvert H. Plummer R, et al. Among authors: calvert h. Clin Cancer Res. 2008 Dec 1;14(23):7917-23. doi: 10.1158/1078-0432.CCR-08-1223. Clin Cancer Res. 2008. PMID: 19047122 Free PMC article. Clinical Trial.
Phase I study of MG98, an oligonucleotide antisense inhibitor of human DNA methyltransferase 1, given as a 7-day infusion in patients with advanced solid tumors.
Plummer R, Vidal L, Griffin M, Lesley M, de Bono J, Coulthard S, Sludden J, Siu LL, Chen EX, Oza AM, Reid GK, McLeod AR, Besterman JM, Lee C, Judson I, Calvert H, Boddy AV. Plummer R, et al. Among authors: calvert h. Clin Cancer Res. 2009 May 1;15(9):3177-83. doi: 10.1158/1078-0432.CCR-08-2859. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383817 Free article. Clinical Trial.
Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers.
Plummer R, Attard G, Pacey S, Li L, Razak A, Perrett R, Barrett M, Judson I, Kaye S, Fox NL, Halpern W, Corey A, Calvert H, de Bono J. Plummer R, et al. Among authors: calvert h. Clin Cancer Res. 2007 Oct 15;13(20):6187-94. doi: 10.1158/1078-0432.CCR-07-0950. Clin Cancer Res. 2007. PMID: 17947486 Clinical Trial.
Temozolomide and treatment of malignant glioma.
Friedman HS, Kerby T, Calvert H. Friedman HS, et al. Among authors: calvert h. Clin Cancer Res. 2000 Jul;6(7):2585-97. Clin Cancer Res. 2000. PMID: 10914698 Review.
Phase 0 clinical trials: recommendations from the Task Force on Methodology for the Development of Innovative Cancer Therapies.
Kummar S, Doroshow JH, Tomaszewski JE, Calvert AH, Lobbezoo M, Giaccone G; Task Force on Methodology for the Development of Innovative Cancer Therapies (MDICT). Kummar S, et al. Among authors: calvert ah. Eur J Cancer. 2009 Mar;45(5):741-6. doi: 10.1016/j.ejca.2008.10.024. Epub 2008 Dec 16. Eur J Cancer. 2009. PMID: 19091546 Free PMC article. Review.
Open-label, non-randomised, inter-individual dose escalation of ZK 304709 with the evaluation of safety, tolerability, pharmacokinetics, oral bioavailability and orientating efficacy after daily administration in patients with advanced cancer (7 d treatment and 14 d recovery).
Graham JS, Plummer R, McCoy C, Kowal K, Wiesinger H, Detjen K, Calvert H, Wiedenmann B, Cassidy J. Graham JS, et al. Among authors: calvert h. Eur J Cancer. 2008 Oct;44(15):2162-8. doi: 10.1016/j.ejca.2008.06.006. Epub 2008 Jul 22. Eur J Cancer. 2008. PMID: 18653327 Clinical Trial.
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