Morgan RA - Search Results

1

Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition.

Yang S, Cohen CJ, Peng PD, Zhao Y, Cassard L, Yu Z, Zheng Z, Jones S, Restifo NP, Rosenberg SA, Morgan RA. Yang S, et al. Among authors: morgan ra. Gene Ther. 2008 Nov;15(21):1411-23. doi: 10.1038/gt.2008.90. Epub 2008 May 22. Gene Ther. 2008. PMID: 18496571 Free PMC article.

2

Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.

Jones S, Peng PD, Yang S, Hsu C, Cohen CJ, Zhao Y, Abad J, Zheng Z, Rosenberg SA, Morgan RA. Jones S, et al. Among authors: morgan ra. Hum Gene Ther. 2009 Jun;20(6):630-40. doi: 10.1089/hum.2008.048. Hum Gene Ther. 2009. PMID: 19265475 Free PMC article.

3

Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation.

Burns WR, Zheng Z, Rosenberg SA, Morgan RA. Burns WR, et al. Among authors: morgan ra. Blood. 2009 Oct 1;114(14):2888-99. doi: 10.1182/blood-2009-01-199216. Epub 2009 Jul 9. Blood. 2009. PMID: 19589923 Free PMC article.

4

Relationship of p53 overexpression on cancers and recognition by anti-p53 T cell receptor-transduced T cells.

Theoret MR, Cohen CJ, Nahvi AV, Ngo LT, Suri KB, Powell DJ Jr, Dudley ME, Morgan RA, Rosenberg SA. Theoret MR, et al. Among authors: morgan ra. Hum Gene Ther. 2008 Nov;19(11):1219-32. doi: 10.1089/hum.2008.083. Hum Gene Ther. 2008. PMID: 19848582 Free PMC article.

5

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.

Morgan RA, Yang JC, Kitano M, Dudley ME, Laurencot CM, Rosenberg SA. Morgan RA, et al. Mol Ther. 2010 Apr;18(4):843-51. doi: 10.1038/mt.2010.24. Epub 2010 Feb 23. Mol Ther. 2010. PMID: 20179677 Free PMC article.

6

Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase.

Frankel TL, Burns WR, Peng PD, Yu Z, Chinnasamy D, Wargo JA, Zheng Z, Restifo NP, Rosenberg SA, Morgan RA. Frankel TL, et al. Among authors: morgan ra. J Immunol. 2010 Jun 1;184(11):5988-98. doi: 10.4049/jimmunol.1000189. Epub 2010 Apr 28. J Immunol. 2010. PMID: 20427771 Free PMC article.

7

A simplified method for the clinical-scale generation of central memory-like CD8+ T cells after transduction with lentiviral vectors encoding antitumor antigen T-cell receptors.

Yang S, Dudley ME, Rosenberg SA, Morgan RA. Yang S, et al. Among authors: morgan ra. J Immunother. 2010 Jul-Aug;33(6):648-58. doi: 10.1097/CJI.0b013e3181e311cb. J Immunother. 2010. PMID: 20551831 Free PMC article.

8

Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment.

Zhang L, Kerkar SP, Yu Z, Zheng Z, Yang S, Restifo NP, Rosenberg SA, Morgan RA. Zhang L, et al. Among authors: morgan ra. Mol Ther. 2011 Apr;19(4):751-9. doi: 10.1038/mt.2010.313. Epub 2011 Feb 1. Mol Ther. 2011. PMID: 21285960 Free PMC article.

9

A simple and effective method to generate lentiviral vectors for ex vivo gene delivery to mature human peripheral blood lymphocytes.

Yang S, Karne NK, Goff SL, Black MA, Xu H, Bischof D, Cornetta K, Rosenberg SA, Morgan RA, Feldman SA. Yang S, et al. Among authors: morgan ra. Hum Gene Ther Methods. 2012 Apr;23(2):73-83. doi: 10.1089/hgtb.2011.199. Epub 2012 Apr 19. Hum Gene Ther Methods. 2012. PMID: 22515320 Free PMC article.

10

Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma.

Morgan RA, Johnson LA, Davis JL, Zheng Z, Woolard KD, Reap EA, Feldman SA, Chinnasamy N, Kuan CT, Song H, Zhang W, Fine HA, Rosenberg SA. Morgan RA, et al. Hum Gene Ther. 2012 Oct;23(10):1043-53. doi: 10.1089/hum.2012.041. Epub 2012 Sep 24. Hum Gene Ther. 2012. PMID: 22780919 Free PMC article.

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