Peterson TR - Search Results

1

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.

Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM. Sancak Y, et al. Among authors: peterson tr. Science. 2008 Jun 13;320(5882):1496-501. doi: 10.1126/science.1157535. Epub 2008 May 22. Science. 2008. PMID: 18497260 Free PMC article.

2

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.

Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM. Peterson TR, et al. Cell. 2009 May 29;137(5):873-86. doi: 10.1016/j.cell.2009.03.046. Epub 2009 May 14. Cell. 2009. PMID: 19446321 Free PMC article.

3

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress.

Sengupta S, Peterson TR, Sabatini DM. Sengupta S, et al. Among authors: peterson tr. Mol Cell. 2010 Oct 22;40(2):310-22. doi: 10.1016/j.molcel.2010.09.026. Mol Cell. 2010. PMID: 20965424 Free PMC article. Review.

4

mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.

Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. Sengupta S, et al. Among authors: peterson tr. Nature. 2010 Dec 23;468(7327):1100-4. doi: 10.1038/nature09584. Nature. 2010. PMID: 21179166

5

The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

Hsu PP, Kang SA, Rameseder J, Zhang Y, Ottina KA, Lim D, Peterson TR, Choi Y, Gray NS, Yaffe MB, Marto JA, Sabatini DM. Hsu PP, et al. Among authors: peterson tr. Science. 2011 Jun 10;332(6035):1317-22. doi: 10.1126/science.1199498. Science. 2011. PMID: 21659604 Free PMC article.

6

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.

Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM. Sancak Y, et al. Among authors: peterson tr. Mol Cell. 2007 Mar 23;25(6):903-15. doi: 10.1016/j.molcel.2007.03.003. Mol Cell. 2007. PMID: 17386266 Free article.

7

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM. Peterson TR, et al. Cell. 2011 Aug 5;146(3):408-20. doi: 10.1016/j.cell.2011.06.034. Cell. 2011. PMID: 21816276 Free PMC article.

8

eIF3: a connecTOR of S6K1 to the translation preinitiation complex.

Peterson TR, Sabatini DM. Peterson TR, et al. Mol Cell. 2005 Dec 9;20(5):655-7. doi: 10.1016/j.molcel.2005.11.016. Mol Cell. 2005. PMID: 16337588 Free article. Review.

9

MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors.

Birsoy K, Wang T, Possemato R, Yilmaz OH, Koch CE, Chen WW, Hutchins AW, Gultekin Y, Peterson TR, Carette JE, Brummelkamp TR, Clish CB, Sabatini DM. Birsoy K, et al. Among authors: peterson tr. Nat Genet. 2013 Jan;45(1):104-8. doi: 10.1038/ng.2471. Epub 2012 Dec 2. Nat Genet. 2013. PMID: 23202129 Free PMC article.

10

Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.

Boulbes D, Chen CH, Shaikenov T, Agarwal NK, Peterson TR, Addona TA, Keshishian H, Carr SA, Magnuson MA, Sabatini DM, Sarbassov dos D. Boulbes D, et al. Among authors: peterson tr. Mol Cancer Res. 2010 Jun;8(6):896-906. doi: 10.1158/1541-7786.MCR-09-0409. Epub 2010 May 25. Mol Cancer Res. 2010. PMID: 20501647 Free PMC article.

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