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Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes.
Soro-Paavonen A, Watson AM, Li J, Paavonen K, Koitka A, Calkin AC, Barit D, Coughlan MT, Drew BG, Lancaster GI, Thomas M, Forbes JM, Nawroth PP, Bierhaus A, Cooper ME, Jandeleit-Dahm KA. Soro-Paavonen A, et al. Among authors: nawroth pp. Diabetes. 2008 Sep;57(9):2461-9. doi: 10.2337/db07-1808. Epub 2008 May 28. Diabetes. 2008. PMID: 18511846 Free PMC article.
RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.
Coughlan MT, Thorburn DR, Penfold SA, Laskowski A, Harcourt BE, Sourris KC, Tan AL, Fukami K, Thallas-Bonke V, Nawroth PP, Brownlee M, Bierhaus A, Cooper ME, Forbes JM. Coughlan MT, et al. Among authors: nawroth pp. J Am Soc Nephrol. 2009 Apr;20(4):742-52. doi: 10.1681/ASN.2008050514. Epub 2009 Jan 21. J Am Soc Nephrol. 2009. PMID: 19158353 Free PMC article.
Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor.
Sourris KC, Morley AL, Koitka A, Samuel P, Coughlan MT, Penfold SA, Thomas MC, Bierhaus A, Nawroth PP, Yamamoto H, Allen TJ, Walther T, Hussain T, Cooper ME, Forbes JM. Sourris KC, et al. Among authors: nawroth pp. Diabetologia. 2010 Nov;53(11):2442-51. doi: 10.1007/s00125-010-1837-2. Epub 2010 Jul 15. Diabetologia. 2010. PMID: 20631980 Free PMC article.
RAGE in inflammation: a new therapeutic target?
Bierhaus A, Stern DM, Nawroth PP. Bierhaus A, et al. Among authors: nawroth pp. Curr Opin Investig Drugs. 2006 Nov;7(11):985-91. Curr Opin Investig Drugs. 2006. PMID: 17117586 Review.
604 results