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Page 1
A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells.
Bagnoli F, Moschioni M, Donati C, Dimitrovska V, Ferlenghi I, Facciotti C, Muzzi A, Giusti F, Emolo C, Sinisi A, Hilleringmann M, Pansegrau W, Censini S, Rappuoli R, Covacci A, Masignani V, Barocchi MA. Bagnoli F, et al. Among authors: emolo c. J Bacteriol. 2008 Aug;190(15):5480-92. doi: 10.1128/JB.00384-08. Epub 2008 May 30. J Bacteriol. 2008. PMID: 18515415 Free PMC article.
The two variants of the Streptococcus pneumoniae pilus 1 RrgA adhesin retain the same function and elicit cross-protection in vivo.
Moschioni M, Emolo C, Biagini M, Maccari S, Pansegrau W, Donati C, Hilleringmann M, Ferlenghi I, Ruggiero P, Sinisi A, Pizza M, Norais N, Barocchi MA, Masignani V. Moschioni M, et al. Among authors: emolo c. Infect Immun. 2010 Dec;78(12):5033-42. doi: 10.1128/IAI.00601-10. Epub 2010 Sep 7. Infect Immun. 2010. PMID: 20823200 Free PMC article.
Structural and functional characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain.
Gentile MA, Melchiorre S, Emolo C, Moschioni M, Gianfaldoni C, Pancotto L, Ferlenghi I, Scarselli M, Pansegrau W, Veggi D, Merola M, Cantini F, Ruggiero P, Banci L, Masignani V. Gentile MA, et al. Among authors: emolo c. J Biol Chem. 2011 Apr 22;286(16):14588-97. doi: 10.1074/jbc.M110.202739. Epub 2011 Mar 2. J Biol Chem. 2011. PMID: 21367860 Free PMC article.