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Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.
De Vos KJ, Chapman AL, Tennant ME, Manser C, Tudor EL, Lau KF, Brownlees J, Ackerley S, Shaw PJ, McLoughlin DM, Shaw CE, Leigh PN, Miller CCJ, Grierson AJ. De Vos KJ, et al. Among authors: mcloughlin dm. Hum Mol Genet. 2007 Nov 15;16(22):2720-2728. doi: 10.1093/hmg/ddm226. Epub 2007 Aug 28. Hum Mol Genet. 2007. PMID: 17725983 Free PMC article.
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth.
Tudor EL, Perkinton MS, Schmidt A, Ackerley S, Brownlees J, Jacobsen NJ, Byers HL, Ward M, Hall A, Leigh PN, Shaw CE, McLoughlin DM, Miller CC. Tudor EL, et al. Among authors: mcloughlin dm. J Biol Chem. 2005 Oct 14;280(41):34735-40. doi: 10.1074/jbc.M506216200. Epub 2005 Jul 26. J Biol Chem. 2005. PMID: 16049005 Free article.
The FE65 proteins and Alzheimer's disease.
McLoughlin DM, Miller CC. McLoughlin DM, et al. J Neurosci Res. 2008 Mar;86(4):744-54. doi: 10.1002/jnr.21532. J Neurosci Res. 2008. PMID: 17828772 Review.
Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.
Tudor EL, Galtrey CM, Perkinton MS, Lau KF, De Vos KJ, Mitchell JC, Ackerley S, Hortobágyi T, Vámos E, Leigh PN, Klasen C, McLoughlin DM, Shaw CE, Miller CC. Tudor EL, et al. Among authors: mcloughlin dm. Neuroscience. 2010 May 19;167(3):774-85. doi: 10.1016/j.neuroscience.2010.02.035. Epub 2010 Feb 24. Neuroscience. 2010. PMID: 20188146
The X11/Mint family of adaptor proteins.
Rogelj B, Mitchell JC, Miller CC, McLoughlin DM. Rogelj B, et al. Among authors: mcloughlin dm. Brain Res Rev. 2006 Sep;52(2):305-15. doi: 10.1016/j.brainresrev.2006.04.005. Epub 2006 Jun 9. Brain Res Rev. 2006. PMID: 16764936 Review.
179 results