Yin Y - Search Results

1

Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex.

Sun A, Yoon JJ, Yin Y, Prussia A, Yang Y, Min J, Plemper RK, Snyder JP. Sun A, et al. Among authors: yin y. J Med Chem. 2008 Jul 10;51(13):3731-41. doi: 10.1021/jm701239a. Epub 2008 Jun 5. J Med Chem. 2008. PMID: 18529043 Free PMC article.

2

Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors.

Feng Y, Yin Y, Weiser A, Griffin E, Cameron MD, Lin L, Ruiz C, Schürer SC, Inoue T, Rao PV, Schröter T, Lograsso P. Feng Y, et al. Among authors: yin y. J Med Chem. 2008 Nov 13;51(21):6642-5. doi: 10.1021/jm800986w. Epub 2008 Oct 4. J Med Chem. 2008. PMID: 18834107 Free PMC article.

3

Tetrahydroisoquinoline derivatives as highly selective and potent Rho kinase inhibitors.

Fang X, Yin Y, Chen YT, Yao L, Wang B, Cameron MD, Lin L, Khan S, Ruiz C, Schröter T, Grant W, Weiser A, Pocas J, Pachori A, Schürer S, Lograsso P, Feng Y. Fang X, et al. Among authors: yin y. J Med Chem. 2010 Aug 12;53(15):5727-37. doi: 10.1021/jm100579r. J Med Chem. 2010. PMID: 20684608

4

Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors.

Yin Y, Zheng K, Eid N, Howard S, Jeong JH, Yi F, Guo J, Park CM, Bibian M, Wu W, Hernandez P, Park H, Wu Y, Luo JL, LoGrasso PV, Feng Y. Yin Y, et al. J Med Chem. 2015 Feb 26;58(4):1846-61. doi: 10.1021/jm501680m. Epub 2015 Feb 4. J Med Chem. 2015. PMID: 25621531 Free PMC article.

5

Discovery of potent and selective urea-based ROCK inhibitors: Exploring the inhibitor's potency and ROCK2/PKA selectivity by 3D-QSAR, molecular docking and molecular dynamics simulations.

Mei D, Yin Y, Wu F, Cui J, Zhou H, Sun G, Jiang Y, Feng Y. Mei D, et al. Among authors: yin y. Bioorg Med Chem. 2015 May 15;23(10):2505-17. doi: 10.1016/j.bmc.2015.03.047. Epub 2015 Mar 25. Bioorg Med Chem. 2015. PMID: 25882521

6

Synthesis and biological evaluation of urea derivatives as highly potent and selective rho kinase inhibitors.

Yin Y, Lin L, Ruiz C, Khan S, Cameron MD, Grant W, Pocas J, Eid N, Park H, Schröter T, Lograsso PV, Feng Y. Yin Y, et al. J Med Chem. 2013 May 9;56(9):3568-81. doi: 10.1021/jm400062r. Epub 2013 Apr 25. J Med Chem. 2013. PMID: 23570561

7

Discovery of bis-aryl urea derivatives as potent and selective Limk inhibitors: Exploring Limk1 activity and Limk1/ROCK2 selectivity through a combined computational study.

Cui J, Ding M, Deng W, Yin Y, Wang Z, Zhou H, Sun G, Jiang Y, Feng Y. Cui J, et al. Among authors: yin y. Bioorg Med Chem. 2015 Dec 1;23(23):7464-77. doi: 10.1016/j.bmc.2015.10.041. Epub 2015 Oct 30. Bioorg Med Chem. 2015. PMID: 26545798

8

Discovery of (S)-6-methoxy-chroman-3-carboxylic acid (4-pyridin-4-yl-phenyl)-amide as potent and isoform selective ROCK2 inhibitors.

Pan J, Yin Y, Zhao L, Feng Y. Pan J, et al. Among authors: yin y. Bioorg Med Chem. 2019 Apr 1;27(7):1382-1390. doi: 10.1016/j.bmc.2019.02.047. Epub 2019 Feb 22. Bioorg Med Chem. 2019. PMID: 30819619

9

Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors.

Yin Y, Lin L, Ruiz C, Cameron MD, Pocas J, Grant W, Schröter T, Chen W, Duckett D, Schürer S, Lograsso P, Feng Y. Yin Y, et al. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6686-90. doi: 10.1016/j.bmcl.2009.09.115. Epub 2009 Oct 3. Bioorg Med Chem Lett. 2009. PMID: 19837589

10

Discovery of (E)-1-amino-4-phenylbut-3-en-2-ol derivatives as novel neuraminidase inhibitors.

Lu C, Yin Y, Meng F, Dun Y, Pei K, Wang C, Xu X, Wu F. Lu C, et al. Among authors: yin y. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2003-2007. doi: 10.1016/j.bmcl.2018.05.002. Epub 2018 May 4. Bioorg Med Chem Lett. 2018. PMID: 29748050

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