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Page 1
Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors.
Hamblin JN, Angell TD, Ballantine SP, Cook CM, Cooper AW, Dawson J, Delves CJ, Jones PS, Lindvall M, Lucas FS, Mitchell CJ, Neu MY, Ranshaw LE, Solanke YE, Somers DO, Wiseman JO. Hamblin JN, et al. Among authors: mitchell cj. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4237-41. doi: 10.1016/j.bmcl.2008.05.052. Epub 2008 May 17. Bioorg Med Chem Lett. 2008. PMID: 18539455
Pyrazolopyridines as potent PDE4B inhibitors: 5-heterocycle SAR.
Mitchell CJ, Ballantine SP, Coe DM, Cook CM, Delves CJ, Dowle MD, Edlin CD, Hamblin JN, Holman S, Johnson MR, Jones PS, Keeling SE, Kranz M, Lindvall M, Lucas FS, Neu M, Solanke YE, Somers DO, Trivedi NA, Wiseman JO. Mitchell CJ, et al. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5803-6. doi: 10.1016/j.bmcl.2010.07.136. Epub 2010 Aug 5. Bioorg Med Chem Lett. 2010. PMID: 20732811
Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors.
Watson NS, Brown D, Campbell M, Chan C, Chaudry L, Convery MA, Fenwick R, Hamblin JN, Haslam C, Kelly HA, King NP, Kurtis CL, Leach AR, Manchee GR, Mason AM, Mitchell C, Patel C, Patel VK, Senger S, Shah GP, Weston HE, Whitworth C, Young RJ. Watson NS, et al. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3784-8. doi: 10.1016/j.bmcl.2006.04.053. Epub 2006 May 11. Bioorg Med Chem Lett. 2006. PMID: 16697194
Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodelling.
Mcleod JC, Lim C, Stokes T, Sharif JA, Zeynalli V, Wiens L, D'Souza AC, Colenso-Semple L, McKendry J, Morton RW, Mitchell CJ, Oikawa SY, Wahlestedt C, Chapple JP, McGlory C, Timmons JA, Phillips SM. Mcleod JC, et al. Among authors: mitchell cj. NAR Mol Med. 2024 Oct 22;1(4):ugae016. doi: 10.1093/narmme/ugae016. eCollection 2024 Oct. NAR Mol Med. 2024. PMID: 39669123 Free PMC article.
Aldosterone-induced salt appetite requires HSD2 neurons.
Gasparini S, Peltekian L, McDonough MC, Mitchell CJ, Hefti M, Resch JM, Geerling JC. Gasparini S, et al. Among authors: mitchell cj. JCI Insight. 2024 Dec 6;9(23):e175087. doi: 10.1172/jci.insight.175087. JCI Insight. 2024. PMID: 39446486 Free PMC article.
Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodelling.
Mcleod JC, Lim C, Stokes T, Sharif JA, Zeynalli V, Wiens L, D'Souza AC, Colenso-Semple L, McKendry J, Morton RW, Mitchell CJ, Oikawa SY, Wahlestedt C, Paul Chapple J, McGlory C, Timmons JA, Phillips SM. Mcleod JC, et al. Among authors: mitchell cj. bioRxiv [Preprint]. 2024 Oct 9:2024.08.11.606848. doi: 10.1101/2024.08.11.606848. bioRxiv. 2024. Update in: NAR Mol Med. 2024 Oct 22;1(4):ugae016. doi: 10.1093/narmme/ugae016 PMID: 39416175 Free PMC article. Updated. Preprint.
392 results