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Page 1
Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.
Pfefferkorn JA, Choi C, Song Y, Trivedi BK, Larsen SD, Askew V, Dillon L, Hanselman JC, Lin Z, Lu G, Robertson A, Sekerke C, Auerbach B, Pavlovsky A, Harris MS, Bainbridge G, Caspers N. Pfefferkorn JA, et al. Among authors: bainbridge g. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4531-7. doi: 10.1016/j.bmcl.2007.05.097. Epub 2007 Jun 6. Bioorg Med Chem Lett. 2007. PMID: 17574411
Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors.
Pfefferkorn JA, Song Y, Sun KL, Miller SR, Trivedi BK, Choi C, Sorenson RJ, Bratton LD, Unangst PC, Larsen SD, Poel TJ, Cheng XM, Lee C, Erasga N, Auerbach B, Askew V, Dillon L, Hanselman JC, Lin Z, Lu G, Robertson A, Olsen K, Mertz T, Sekerke C, Pavlovsky A, Harris MS, Bainbridge G, Caspers N, Chen H, Eberstadt M. Pfefferkorn JA, et al. Among authors: bainbridge g. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4538-44. doi: 10.1016/j.bmcl.2007.05.096. Epub 2007 Jun 6. Bioorg Med Chem Lett. 2007. PMID: 17574412
Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.
Pfefferkorn JA, Choi C, Larsen SD, Auerbach B, Hutchings R, Park W, Askew V, Dillon L, Hanselman JC, Lin Z, Lu GH, Robertson A, Sekerke C, Harris MS, Pavlovsky A, Bainbridge G, Caspers N, Kowala M, Tait BD. Pfefferkorn JA, et al. Among authors: bainbridge g. J Med Chem. 2008 Jan 10;51(1):31-45. doi: 10.1021/jm070849r. Epub 2007 Dec 12. J Med Chem. 2008. PMID: 18072721
A quantitative evaluation of aerosol generation during awake tracheal intubation.
Shrimpton AJ, O'Farrell G, Howes HM, Craven R, Duffen AR, Cook TM, Reid JP, Brown JM, Pickering AE; Bristol Awake Fibre-Optic Intubation Collective. Shrimpton AJ, et al. Anaesthesia. 2023 May;78(5):587-597. doi: 10.1111/anae.15968. Epub 2023 Jan 29. Anaesthesia. 2023. PMID: 36710390 Free article.
FeMV is a cathepsin-dependent unique morbillivirus infecting the kidneys of domestic cats.
Nambulli S, Rennick LJ, Acciardo AS, Tilston-Lunel NL, Ho G, Crossland NA, Hardcastle K, Nieto B, Bainbridge G, Williams T, Sharp CR, Duprex WP. Nambulli S, et al. Among authors: bainbridge g. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2209405119. doi: 10.1073/pnas.2209405119. Epub 2022 Oct 17. Proc Natl Acad Sci U S A. 2022. PMID: 36251995 Free PMC article.
Bias, Repeatability and Reproducibility of Liver T1 Mapping With Variable Flip Angles.
Tadimalla S, Wilson DJ, Shelley D, Bainbridge G, Saysell M, Mendichovszky IA, Graves MJ, Guthrie JA, Waterton JC, Parker GJM, Sourbron SP. Tadimalla S, et al. Among authors: bainbridge g. J Magn Reson Imaging. 2022 Oct;56(4):1042-1052. doi: 10.1002/jmri.28127. Epub 2022 Feb 27. J Magn Reson Imaging. 2022. PMID: 35224803 Free PMC article.
Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor.
Gow DJ, Sauter KA, Pridans C, Moffat L, Sehgal A, Stutchfield BM, Raza S, Beard PM, Tsai YT, Bainbridge G, Boner PL, Fici G, Garcia-Tapia D, Martin RA, Oliphant T, Shelly JA, Tiwari R, Wilson TL, Smith LB, Mabbott NA, Hume DA. Gow DJ, et al. Among authors: bainbridge g. Mol Ther. 2014 Sep;22(9):1580-92. doi: 10.1038/mt.2014.112. Epub 2014 Jun 25. Mol Ther. 2014. PMID: 24962162 Free PMC article.
30 results