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Synthesis and in vitro antimycobacterial activity of 3-substituted 5-hydroxy-5-trifluoro[chloro]methyl-4,5-dihydro-1H-1-(isonicotinoyl) pyrazoles.
Almeida da Silva PE, Ramos DF, Bonacorso HG, de la Iglesia AI, Oliveira MR, Coelho T, Navarini J, Morbidoni HR, Zanatta N, Martins MA. Almeida da Silva PE, et al. Among authors: morbidoni hr. Int J Antimicrob Agents. 2008 Aug;32(2):139-44. doi: 10.1016/j.ijantimicag.2008.03.019. Epub 2008 Jun 20. Int J Antimicrob Agents. 2008. PMID: 18571384
IQG-607 abrogates the synthesis of mycolic acids and displays intracellular activity against Mycobacterium tuberculosis in infected macrophages.
Rodrigues-Junior VS, dos Santos Junior AA, Villela AD, Belardinelli JM, Morbidoni HR, Basso LA, Campos MM, Santos DS. Rodrigues-Junior VS, et al. Among authors: morbidoni hr. Int J Antimicrob Agents. 2014 Jan;43(1):82-5. doi: 10.1016/j.ijantimicag.2013.08.021. Epub 2013 Oct 1. Int J Antimicrob Agents. 2014. PMID: 24139881
Antitubercular activity of 1,2,3-triazolyl fatty acid derivatives.
Ghiano DG, de la Iglesia A, Liu N, Tonge PJ, Morbidoni HR, Labadie GR. Ghiano DG, et al. Among authors: morbidoni hr. Eur J Med Chem. 2017 Jan 5;125:842-852. doi: 10.1016/j.ejmech.2016.09.086. Epub 2016 Sep 28. Eur J Med Chem. 2017. PMID: 27750201 Free PMC article.
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