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Page 1
Pathogenic ATM mutations occur rarely in a subset of multiple myeloma patients.
Austen B, Barone G, Reiman A, Byrd PJ, Baker C, Starczynski J, Nobbs MC, Murphy RP, Enright H, Chaila E, Quinn J, Stankovic T, Pratt G, Taylor AM. Austen B, et al. Among authors: taylor am. Br J Haematol. 2008 Sep;142(6):925-33. doi: 10.1111/j.1365-2141.2008.07281.x. Epub 2008 Jun 28. Br J Haematol. 2008. PMID: 18573109 Free article.
Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias.
Starczynski J, Simmons W, Flavell JR, Byrd PJ, Stewart GS, Kullar HS, Groom A, Crocker J, Moss PA, Reynolds GM, Glavina-Durdov M, Taylor AM, Fegan C, Stankovic T, Murray PG. Starczynski J, et al. Among authors: taylor am. Am J Pathol. 2003 Aug;163(2):423-32. doi: 10.1016/S0002-9440(10)63672-3. Am J Pathol. 2003. PMID: 12875964 Free PMC article.
Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses.
Stankovic T, Hubank M, Cronin D, Stewart GS, Fletcher D, Bignell CR, Alvi AJ, Austen B, Weston VJ, Fegan C, Byrd PJ, Moss PA, Taylor AM. Stankovic T, et al. Among authors: taylor am. Blood. 2004 Jan 1;103(1):291-300. doi: 10.1182/blood-2003-04-1161. Epub 2003 Sep 4. Blood. 2004. PMID: 12958068 Free article.
A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival.
Alvi AJ, Austen B, Weston VJ, Fegan C, MacCallum D, Gianella-Borradori A, Lane DP, Hubank M, Powell JE, Wei W, Taylor AM, Moss PA, Stankovic T. Alvi AJ, et al. Among authors: taylor am. Blood. 2005 Jun 1;105(11):4484-91. doi: 10.1182/blood-2004-07-2713. Epub 2005 Feb 3. Blood. 2005. PMID: 15692065 Free article.
Biallelic ATM inactivation significantly reduces survival in patients treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 trial.
Skowronska A, Parker A, Ahmed G, Oldreive C, Davis Z, Richards S, Dyer M, Matutes E, Gonzalez D, Taylor AM, Moss P, Thomas P, Oscier D, Stankovic T. Skowronska A, et al. Among authors: taylor am. J Clin Oncol. 2012 Dec 20;30(36):4524-32. doi: 10.1200/JCO.2011.41.0852. Epub 2012 Oct 22. J Clin Oncol. 2012. PMID: 23091097 Clinical Trial.
1,002 results