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Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts.
Chen Y, Leask A, Abraham DJ, Pala D, Shiwen X, Khan K, Liu S, Carter DE, Wilcox-Adelman S, Goetinck P, Denton CP, Black CM, Pitsillides AA, Sarraf CE, Eastwood M. Chen Y, et al. Among authors: liu s. Arthritis Rheum. 2008 Feb;58(2):577-85. doi: 10.1002/art.23146. Arthritis Rheum. 2008. PMID: 18240216 Free article.
mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis.
McCann MR, Monemdjou R, Ghassemi-Kakroodi P, Fahmi H, Perez G, Liu S, Shi-Wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M. McCann MR, et al. Among authors: liu s. Arthritis Res Ther. 2011;13(1):R6. doi: 10.1186/ar3226. Epub 2011 Jan 25. Arthritis Res Ther. 2011. PMID: 21266028 Free PMC article.
Integrin β1 is required for dermal homeostasis.
Liu S, Leask A. Liu S, et al. J Invest Dermatol. 2013 Apr;133(4):899-906. doi: 10.1038/jid.2012.438. Epub 2012 Nov 29. J Invest Dermatol. 2013. PMID: 23190902 Free article.
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