DeVoss JJ - Search Results

1

Re-engineering of CYP2C9 to probe acid-base substrate selectivity.

Tai G, Dickmann LJ, Matovic N, DeVoss JJ, Gillam EM, Rettie AE. Tai G, et al. Among authors: devoss jj. Drug Metab Dispos. 2008 Oct;36(10):1992-7. doi: 10.1124/dmd.108.022186. Epub 2008 Jul 7. Drug Metab Dispos. 2008. PMID: 18606741 Free PMC article.

2

Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.

Munns AJ, De Voss JJ, Hooper WD, Dickinson RG, Gillam EM. Munns AJ, et al. Chem Res Toxicol. 1997 Sep;10(9):1049-58. doi: 10.1021/tx9700836. Chem Res Toxicol. 1997. PMID: 9305589

3

Oxidation of indole by cytochrome P450 enzymes.

Gillam EM, Notley LM, Cai H, De Voss JJ, Guengerich FP. Gillam EM, et al. Biochemistry. 2000 Nov 14;39(45):13817-24. doi: 10.1021/bi001229u. Biochemistry. 2000. PMID: 11076521

4

Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).

Davies C, Witham K, Scott JR, Pearson A, DeVoss JJ, Graham SE, Gillam EM. Davies C, et al. Among authors: devoss jj. Drug Metab Dispos. 2004 Apr;32(4):431-6. doi: 10.1124/dmd.32.4.431. Drug Metab Dispos. 2004. PMID: 15039296

5

Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes.

Matthias A, Gillam EM, Penman KG, Matovic NJ, Bone KM, De Voss JJ, Lehmann RP. Matthias A, et al. Chem Biol Interact. 2005 Jun 30;155(1-2):62-70. doi: 10.1016/j.cbi.2005.04.003. Chem Biol Interact. 2005. PMID: 15885678

6

Are branched chain fatty acids the natural substrates for P450(BM3)?

Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Cryle MJ, et al. Chem Commun (Camb). 2006 Jun 14;(22):2353-5. doi: 10.1039/b601202g. Epub 2006 Mar 30. Chem Commun (Camb). 2006. PMID: 16733577

7

Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites.

Avent KM, DeVoss JJ, Gillam EM. Avent KM, et al. Among authors: devoss jj. Chem Res Toxicol. 2006 Jul;19(7):914-20. doi: 10.1021/tx0600090. Chem Res Toxicol. 2006. PMID: 16841959

8

Stereoselective synthesis, natural occurrence and CB(2) receptor binding affinities of alkylamides from herbal medicines such as Echinacea sp.

Matovic N, Matthias A, Gertsch J, Raduner S, Bone KM, Lehmann RP, Devoss JJ. Matovic N, et al. Among authors: devoss jj. Org Biomol Chem. 2007 Jan 7;5(1):169-74. doi: 10.1039/b615487e. Epub 2006 Nov 29. Org Biomol Chem. 2007. PMID: 17164922

9

Extending the diversity of cytochrome P450 enzymes by DNA family shuffling.

Rosic NN, Huang W, Johnston WA, DeVoss JJ, Gillam EM. Rosic NN, et al. Among authors: devoss jj. Gene. 2007 Jun 15;395(1-2):40-8. doi: 10.1016/j.gene.2007.01.031. Epub 2007 Feb 20. Gene. 2007. PMID: 17400405

10

A shuffled CYP1A library shows both structural integrity and functional diversity.

Johnston WA, Huang W, De Voss JJ, Hayes MA, Gillam EM. Johnston WA, et al. Drug Metab Dispos. 2007 Dec;35(12):2177-85. doi: 10.1124/dmd.107.017939. Epub 2007 Sep 6. Drug Metab Dispos. 2007. PMID: 17823232

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