Gillam EM - Search Results

1

Re-engineering of CYP2C9 to probe acid-base substrate selectivity.

Tai G, Dickmann LJ, Matovic N, DeVoss JJ, Gillam EM, Rettie AE. Tai G, et al. Among authors: gillam em. Drug Metab Dispos. 2008 Oct;36(10):1992-7. doi: 10.1124/dmd.108.022186. Epub 2008 Jul 7. Drug Metab Dispos. 2008. PMID: 18606741 Free PMC article.

2

Strigolactones and Shoot Branching: What Is the Real Hormone and How Does It Work?

Dun EA, Brewer PB, Gillam EMJ, Beveridge CA. Dun EA, et al. Among authors: gillam emj. Plant Cell Physiol. 2023 Sep 15;64(9):967-983. doi: 10.1093/pcp/pcad088. Plant Cell Physiol. 2023. PMID: 37526426 Free PMC article. Review.

3

Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.

Munns AJ, De Voss JJ, Hooper WD, Dickinson RG, Gillam EM. Munns AJ, et al. Among authors: gillam em. Chem Res Toxicol. 1997 Sep;10(9):1049-58. doi: 10.1021/tx9700836. Chem Res Toxicol. 1997. PMID: 9305589

4

Oxidation of indole by cytochrome P450 enzymes.

Gillam EM, Notley LM, Cai H, De Voss JJ, Guengerich FP. Gillam EM, et al. Biochemistry. 2000 Nov 14;39(45):13817-24. doi: 10.1021/bi001229u. Biochemistry. 2000. PMID: 11076521

5

Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group.

Cheesman MJ, Baer BR, Zheng YM, Gillam EM, Rettie AE. Cheesman MJ, et al. Among authors: gillam em. Arch Biochem Biophys. 2003 Aug 1;416(1):17-24. doi: 10.1016/s0003-9861(03)00278-9. Arch Biochem Biophys. 2003. PMID: 12859977

6

Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).

Davies C, Witham K, Scott JR, Pearson A, DeVoss JJ, Graham SE, Gillam EM. Davies C, et al. Among authors: gillam em. Drug Metab Dispos. 2004 Apr;32(4):431-6. doi: 10.1124/dmd.32.4.431. Drug Metab Dispos. 2004. PMID: 15039296

7

Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes.

Matthias A, Gillam EM, Penman KG, Matovic NJ, Bone KM, De Voss JJ, Lehmann RP. Matthias A, et al. Among authors: gillam em. Chem Biol Interact. 2005 Jun 30;155(1-2):62-70. doi: 10.1016/j.cbi.2005.04.003. Chem Biol Interact. 2005. PMID: 15885678

8

Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites.

Avent KM, DeVoss JJ, Gillam EM. Avent KM, et al. Among authors: gillam em. Chem Res Toxicol. 2006 Jul;19(7):914-20. doi: 10.1021/tx0600090. Chem Res Toxicol. 2006. PMID: 16841959

9

Extending the diversity of cytochrome P450 enzymes by DNA family shuffling.

Rosic NN, Huang W, Johnston WA, DeVoss JJ, Gillam EM. Rosic NN, et al. Among authors: gillam em. Gene. 2007 Jun 15;395(1-2):40-8. doi: 10.1016/j.gene.2007.01.031. Epub 2007 Feb 20. Gene. 2007. PMID: 17400405

10

A shuffled CYP1A library shows both structural integrity and functional diversity.

Johnston WA, Huang W, De Voss JJ, Hayes MA, Gillam EM. Johnston WA, et al. Among authors: gillam em. Drug Metab Dispos. 2007 Dec;35(12):2177-85. doi: 10.1124/dmd.107.017939. Epub 2007 Sep 6. Drug Metab Dispos. 2007. PMID: 17823232

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