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The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions.
Young JA, Becker AM, Medeiros JJ, Shapiro VS, Wang A, Farrar JD, Quill TA, Hooft van Huijsduijnen R, van Oers NS. Young JA, et al. Among authors: medeiros jj. Mol Immunol. 2008 Aug;45(14):3756-66. doi: 10.1016/j.molimm.2008.05.023. Epub 2008 Jul 9. Mol Immunol. 2008. PMID: 18614237 Free PMC article.
Dynamic modulation of thymic microRNAs in response to stress.
Belkaya S, Silge RL, Hoover AR, Medeiros JJ, Eitson JL, Becker AM, de la Morena MT, Bassel-Duby RS, van Oers NS. Belkaya S, et al. Among authors: medeiros jj. PLoS One. 2011;6(11):e27580. doi: 10.1371/journal.pone.0027580. Epub 2011 Nov 16. PLoS One. 2011. PMID: 22110677 Free PMC article.
Mutations in myeloid transcription factors and activated signaling genes predict chronic myeloid leukemia outcomes.
Perusini MA, Žáčková D, Kim T, Pagnano K, Pavlovsky C, Ježíšková I, Kvetková A, Jurček T, Kim J, Yoo Y, Yi S, Lee H, Kim KH, Chang M, Capo-Chichi JM, Medeiros JJF, Arruda A, Minden M, Zhang Z, Abelson S, Mayer J, Hwan Kim DD. Perusini MA, et al. Among authors: medeiros jjf. Blood Adv. 2024 May 28;8(10):2361-2372. doi: 10.1182/bloodadvances.2023012127. Blood Adv. 2024. PMID: 38447114 Free PMC article.
Clinical significance of clonal hematopoiesis in the setting of autologous stem cell transplantation for lymphoma.
Lackraj T, Ben Barouch S, Medeiros JJF, Pedersen S, Danesh A, Bakhtiari M, Hong M, Tong K, Joynt J, Arruda A, Minden MD, Kuruvilla J, Bhella S, Kukreti V, Crump M, Prica A, Chen C, Deng Y, Xu W, Pugh TJ, Keating A, Dick JE, Abelson S, Kridel R. Lackraj T, et al. Among authors: medeiros jjf. Am J Hematol. 2022 Dec;97(12):1538-1547. doi: 10.1002/ajh.26726. Epub 2022 Sep 26. Am J Hematol. 2022. PMID: 36087071 Free article.
Clonal haematopoiesis is associated with higher mortality in patients with cardiogenic shock.
Scolari FL, Abelson S, Brahmbhatt DH, Medeiros JJF, Fan CS, Fung NL, Mihajlovic V, Anker MS, Otsuki M, Lawler PR, Ross HJ, Luk AC, Anker S, Dick JE, Billia F. Scolari FL, et al. Among authors: medeiros jjf. Eur J Heart Fail. 2022 Sep;24(9):1573-1582. doi: 10.1002/ejhf.2588. Epub 2022 Jul 10. Eur J Heart Fail. 2022. PMID: 35729851 Free article.
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