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The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions.
Young JA, Becker AM, Medeiros JJ, Shapiro VS, Wang A, Farrar JD, Quill TA, Hooft van Huijsduijnen R, van Oers NS. Young JA, et al. Among authors: shapiro vs. Mol Immunol. 2008 Aug;45(14):3756-66. doi: 10.1016/j.molimm.2008.05.023. Epub 2008 Jul 9. Mol Immunol. 2008. PMID: 18614237 Free PMC article.
Chromatin-Modifying Enzymes in T Cell Development.
Shapiro MJ, Shapiro VS. Shapiro MJ, et al. Among authors: shapiro vs. Annu Rev Immunol. 2020 Apr 26;38:397-419. doi: 10.1146/annurev-immunol-092719-082622. Epub 2020 Jan 28. Annu Rev Immunol. 2020. PMID: 31990620 Review.
Histone Deacetylase 3 Is Required for T Cell Maturation.
Hsu FC, Belmonte PJ, Constans MM, Chen MW, McWilliams DC, Hiebert SW, Shapiro VS. Hsu FC, et al. Among authors: shapiro vs. J Immunol. 2015 Aug 15;195(4):1578-90. doi: 10.4049/jimmunol.1500435. Epub 2015 Jul 10. J Immunol. 2015. PMID: 26163592 Free PMC article.
66 results