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New roles for TIM family members in immune regulation.
Kuchroo VK, Dardalhon V, Xiao S, Anderson AC. Kuchroo VK, et al. Among authors: xiao s. Nat Rev Immunol. 2008 Aug;8(8):577-80. doi: 10.1038/nri2366. Nat Rev Immunol. 2008. PMID: 18617884 Review.
Tim-2 regulates T helper type 2 responses and autoimmunity.
Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Chakravarti S, et al. Among authors: xiao s. J Exp Med. 2005 Aug 1;202(3):437-44. doi: 10.1084/jem.20050308. Epub 2005 Jul 25. J Exp Med. 2005. PMID: 16043519 Free PMC article.
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.
Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, Akiba H, Strom T, Sayegh MH, DeKruyff RH, Khoury SJ, Kuchroo VK. Xiao S, et al. J Exp Med. 2007 Jul 9;204(7):1691-702. doi: 10.1084/jem.20062498. Epub 2007 Jul 2. J Exp Med. 2007. PMID: 17606630 Free PMC article.
T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice.
Rodriguez-Manzanet R, Sanjuan MA, Wu HY, Quintana FJ, Xiao S, Anderson AC, Weiner HL, Green DR, Kuchroo VK. Rodriguez-Manzanet R, et al. Among authors: xiao s. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8706-11. doi: 10.1073/pnas.0910359107. Epub 2010 Apr 5. Proc Natl Acad Sci U S A. 2010. PMID: 20368430 Free PMC article.
Aiolos promotes TH17 differentiation by directly silencing Il2 expression.
Quintana FJ, Jin H, Burns EJ, Nadeau M, Yeste A, Kumar D, Rangachari M, Zhu C, Xiao S, Seavitt J, Georgopoulos K, Kuchroo VK. Quintana FJ, et al. Among authors: xiao s. Nat Immunol. 2012 Jul 1;13(8):770-7. doi: 10.1038/ni.2363. Nat Immunol. 2012. PMID: 22751139 Free PMC article.
7,631 results