Lusso P - Search Results

1

Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.

Stricher F, Huang CC, Descours A, Duquesnoy S, Combes O, Decker JM, Kwon YD, Lusso P, Shaw GM, Vita C, Kwong PD, Martin L. Stricher F, et al. Among authors: lusso p. J Mol Biol. 2008 Oct 3;382(2):510-24. doi: 10.1016/j.jmb.2008.06.069. Epub 2008 Jul 1. J Mol Biol. 2008. PMID: 18619974 Free PMC article.

2

Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer.

Zhang P, Gorman J, Geng H, Liu Q, Lin Y, Tsybovsky Y, Go EP, Dey B, Andine T, Kwon A, Patel M, Gururani D, Uddin F, Guzzo C, Cimbro R, Miao H, McKee K, Chuang GY, Martin L, Sironi F, Malnati MS, Desaire H, Berger EA, Mascola JR, Dolan MA, Kwong PD, Lusso P. Zhang P, et al. Among authors: lusso p. Cell Host Microbe. 2018 Jun 13;23(6):832-844.e6. doi: 10.1016/j.chom.2018.05.002. Cell Host Microbe. 2018. PMID: 29902444 Free PMC article.

3

Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes.

Martin L, Stricher F, Missé D, Sironi F, Pugnière M, Barthe P, Prado-Gotor R, Freulon I, Magne X, Roumestand C, Ménez A, Lusso P, Veas F, Vita C. Martin L, et al. Among authors: lusso p. Nat Biotechnol. 2003 Jan;21(1):71-6. doi: 10.1038/nbt768. Epub 2002 Dec 16. Nat Biotechnol. 2003. PMID: 12483221

4

Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.

Liu Q, Acharya P, Dolan MA, Zhang P, Guzzo C, Lu J, Kwon A, Gururani D, Miao H, Bylund T, Chuang GY, Druz A, Zhou T, Rice WJ, Wigge C, Carragher B, Potter CS, Kwong PD, Lusso P. Liu Q, et al. Among authors: lusso p. Nat Struct Mol Biol. 2017 Apr;24(4):370-378. doi: 10.1038/nsmb.3382. Epub 2017 Feb 20. Nat Struct Mol Biol. 2017. PMID: 28218750 Free PMC article.

5

Rational Engraftment of Quaternary-Interactive Acidic Loops for Anti-HIV-1 Antibody Improvement.

Liu Q, Zhang P, Miao H, Lin Y, Kwon YD, Kwong PD, Rikhtegaran-Tehrani Z, Seaman MS, DeVico AL, Sajadi MM, Lusso P. Liu Q, et al. Among authors: lusso p. J Virol. 2021 May 24;95(12):e00159-21. doi: 10.1128/JVI.00159-21. Print 2021 May 24. J Virol. 2021. PMID: 33827946 Free PMC article.

6

Corrigendum: Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.

Liu Q, Acharya P, Dolan MA, Zhang P, Guzzo C, Lu J, Kwon A, Gururani D, Miao H, Bylund T, Chuang GY, Druz A, Zhou T, Rice WJ, Wigge C, Carragher B, Potter CS, Kwong PD, Lusso P. Liu Q, et al. Among authors: lusso p. Nat Struct Mol Biol. 2017 Jun 6;24(6):553. doi: 10.1038/nsmb0617-553b. Nat Struct Mol Biol. 2017. PMID: 28586323 No abstract available.

7

Improvement of antibody functionality by structure-guided paratope engraftment.

Liu Q, Lai YT, Zhang P, Louder MK, Pegu A, Rawi R, Asokan M, Chen X, Shen CH, Chuang GY, Yang ES, Miao H, Wang Y, Fauci AS, Kwong PD, Mascola JR, Lusso P. Liu Q, et al. Among authors: lusso p. Nat Commun. 2019 Feb 13;10(1):721. doi: 10.1038/s41467-019-08658-4. Nat Commun. 2019. PMID: 30760721 Free PMC article.

8

A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention.

Kwon YD, Asokan M, Gorman J, Zhang B, Liu Q, Louder MK, Lin BC, McKee K, Pegu A, Verardi R, Yang ES, Program VP, Carlton K, Doria-Rose NA, Lusso P, Mascola JR, Kwong PD. Kwon YD, et al. Among authors: lusso p. MAbs. 2021 Jan-Dec;13(1):1946918. doi: 10.1080/19420862.2021.1946918. MAbs. 2021. PMID: 34328065 Free PMC article. Review.

9

Design of HIV Coreceptor Derived Peptides That Inhibit Viral Entry at Submicromolar Concentrations.

Bobyk KD, Mandadapu SR, Lohith K, Guzzo C, Bhargava A, Lusso P, Bewley CA. Bobyk KD, et al. Among authors: lusso p. Mol Pharm. 2017 Aug 7;14(8):2681-2689. doi: 10.1021/acs.molpharmaceut.7b00155. Epub 2017 Jul 13. Mol Pharm. 2017. PMID: 28494151 Free PMC article.

10

Recognition of RANTES by extracellular parts of the CCR5 receptor.

Duma L, Häussinger D, Rogowski M, Lusso P, Grzesiek S. Duma L, et al. Among authors: lusso p. J Mol Biol. 2007 Jan 26;365(4):1063-75. doi: 10.1016/j.jmb.2006.10.040. Epub 2006 Oct 17. J Mol Biol. 2007. PMID: 17101151

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