Conner AC - Search Results

1

Functional and biophysical analysis of the C-terminus of the CGRP-receptor; a family B GPCR.

Conner M, Hicks MR, Dafforn T, Knowles TJ, Ludwig C, Staddon S, Overduin M, Günther UL, Thome J, Wheatley M, Poyner DR, Conner AC. Conner M, et al. Among authors: conner ac. Biochemistry. 2008 Aug 12;47(32):8434-44. doi: 10.1021/bi8004126. Epub 2008 Jul 18. Biochemistry. 2008. PMID: 18636754

2

Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function.

Barwell J, Conner A, Poyner DR. Barwell J, et al. Biochim Biophys Acta. 2011 Oct;1813(10):1906-16. doi: 10.1016/j.bbamcr.2011.06.005. Epub 2011 Jun 16. Biochim Biophys Acta. 2011. PMID: 21703310 Free PMC article.

3

A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors.

Conner AC, Hay DL, Simms J, Howitt SG, Schindler M, Smith DM, Wheatley M, Poyner DR. Conner AC, et al. Mol Pharmacol. 2005 Jan;67(1):20-31. Mol Pharmacol. 2005. PMID: 15615699

4

Diverse functional motifs within the three intracellular loops of the CGRP1 receptor.

Conner AC, Simms J, Conner MT, Wootten DL, Wheatley M, Poyner DR. Conner AC, et al. Among authors: conner mt. Biochemistry. 2006 Oct 31;45(43):12976-85. doi: 10.1021/bi0615801. Biochemistry. 2006. PMID: 17059214

5

Characterization of CGRP receptor binding.

Conner AC, Hay DL, Poyner DR. Conner AC, et al. Curr Protoc Pharmacol. 2004 Sep 1;Chapter 1:Unit 1.30. doi: 10.1002/0471141755.ph0130s25. Curr Protoc Pharmacol. 2004. PMID: 22294116

6

The role of the extracellular loops of the CGRP receptor, a family B GPCR.

Barwell J, Woolley MJ, Wheatley M, Conner AC, Poyner DR. Barwell J, et al. Among authors: conner ac. Biochem Soc Trans. 2012 Apr;40(2):433-7. doi: 10.1042/BST20110726. Biochem Soc Trans. 2012. PMID: 22435826 Review.

7

The activation of the CGRP receptor.

Barwell J, Wheatley M, Conner AC, Taddese B, Vohra S, Reynolds CA, Poyner DR. Barwell J, et al. Among authors: conner ac. Biochem Soc Trans. 2013 Feb 1;41(1):180-4. doi: 10.1042/BST20120251. Biochem Soc Trans. 2013. PMID: 23356280 Review.

8

Relative Antagonism of Mutants of the CGRP Receptor Extracellular Loop 2 Domain (ECL2) Using a Truncated Competitive Antagonist (CGRP_8-37): Evidence for the Dual Involvement of ECL2 in the Two-Domain Binding Model.

Woolley MJ, Simms J, Uddin S, Poyner DR, Conner AC. Woolley MJ, et al. Among authors: conner ac. Biochemistry. 2017 Aug 1;56(30):3877-3880. doi: 10.1021/acs.biochem.7b00077. Epub 2017 Jul 18. Biochemistry. 2017. PMID: 28691801

9

Heterodimers and family-B GPCRs: RAMPs, CGRP and adrenomedullin.

Conner AC, Simms J, Hay DL, Mahmoud K, Howitt SG, Wheatley M, Poyner DR. Conner AC, et al. Biochem Soc Trans. 2004 Nov;32(Pt 5):843-6. doi: 10.1042/BST0320843. Biochem Soc Trans. 2004. PMID: 15494030 Review.

10

Ligand binding and activation of the CGRP receptor.

Conner AC, Simms J, Barwell J, Wheatley M, Poyner DR. Conner AC, et al. Biochem Soc Trans. 2007 Aug;35(Pt 4):729-32. doi: 10.1042/BST0350729. Biochem Soc Trans. 2007. PMID: 17635135 Review.

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