Luffer-Atlas D - Search Results

1

Unique/major human metabolites: why, how, and when to test for safety in animals.

Luffer-Atlas D. Luffer-Atlas D. Drug Metab Rev. 2008;40(3):447-63. doi: 10.1080/03602530802186561. Drug Metab Rev. 2008. PMID: 18642142 Review.

2

Predicting circulating human metabolites: how good are we?

Anderson S, Luffer-Atlas D, Knadler MP. Anderson S, et al. Chem Res Toxicol. 2009 Feb;22(2):243-56. doi: 10.1021/tx8004086. Chem Res Toxicol. 2009. PMID: 19138063

3

The early estimation of circulating drug metabolites in humans.

Luffer-Atlas D. Luffer-Atlas D. Expert Opin Drug Metab Toxicol. 2012 Aug;8(8):985-97. doi: 10.1517/17425255.2012.693159. Epub 2012 Jun 10. Expert Opin Drug Metab Toxicol. 2012. PMID: 22681256 Review.

4

Overview of metabolite safety testing from an industry perspective.

Anderson S, Knadler MP, Luffer-Atlas D. Anderson S, et al. Bioanalysis. 2010 Jul;2(7):1249-61. doi: 10.4155/bio.10.67. Bioanalysis. 2010. PMID: 21083238 Review.

5

A decade of drug metabolite safety testing: industry and regulatory shared learning.

Luffer-Atlas D, Atrakchi A. Luffer-Atlas D, et al. Expert Opin Drug Metab Toxicol. 2017 Sep;13(9):897-900. doi: 10.1080/17425255.2017.1364362. Epub 2017 Aug 11. Expert Opin Drug Metab Toxicol. 2017. PMID: 28797172 No abstract available.

6

Orally active inhibitors of human leukocyte elastase. III. Identification and characterization of metabolites of L-694,458 by liquid chromatography-tandem mass spectrometry.

Luffer-Atlas D, Vincent SH, Painter SK, Arison BH, Stearns RA, Chiu SH. Luffer-Atlas D, et al. Drug Metab Dispos. 1997 Aug;25(8):940-52. Drug Metab Dispos. 1997. PMID: 9280402

7

A strategy for the risk assessment of human genotoxic metabolites.

Dobo KL, Obach RS, Luffer-Atlas D, Bercu JP. Dobo KL, et al. Chem Res Toxicol. 2009 Feb;22(2):348-56. doi: 10.1021/tx8004339. Chem Res Toxicol. 2009. PMID: 19170655

8

A radiocalibration method with pseudo internal standard to estimate circulating metabolite concentrations.

Yi P, Luffer-Atlas D. Yi P, et al. Bioanalysis. 2010 Jul;2(7):1195-210. doi: 10.4155/bio.10.81. Bioanalysis. 2010. PMID: 21083234

9

Orally active inhibitors of human leukocyte elastase. II. Disposition of L-694,458 in rats and rhesus monkeys.

Vincent SH, Painter SK, Luffer-Atlas D, Karanam BV, McGowan E, Cioffe C, Doss G, Chiu SH. Vincent SH, et al. Drug Metab Dispos. 1997 Aug;25(8):932-9. Drug Metab Dispos. 1997. PMID: 9280401

10

Orally active inhibitors of human leukocyte elastase. I. Disposition of L-683,845 in rats and rhesus monkeys.

Vincent SH, Painter SK, Krieter PA, Colletti AE, Lyszack E, Rosegay A, Dean D, Luffer-Atlas D, Miller RR, Cioffe C, Chiu SH. Vincent SH, et al. Drug Metab Dispos. 1996 Dec;24(12):1369-77. Drug Metab Dispos. 1996. PMID: 8971144

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