Langaee T - Search Results

1

Role of dichloroacetate in the treatment of genetic mitochondrial diseases.

Stacpoole PW, Kurtz TL, Han Z, Langaee T. Stacpoole PW, et al. Among authors: langaee t. Adv Drug Deliv Rev. 2008 Oct-Nov;60(13-14):1478-87. doi: 10.1016/j.addr.2008.02.014. Epub 2008 Jul 4. Adv Drug Deliv Rev. 2008. PMID: 18647626 Free PMC article. Review.

2

Characterizing OPRM1 DNA methylation in prescription opioid users with chronic musculoskeletal pain.

Sheikh S, Smotherman C, Patel M, Langaee T, Wang D, Swaray E, Velasquez E, Schmidt SOF, Hendry P, Cavallari LH, Fillingim RB. Sheikh S, et al. Among authors: langaee t. Pain Rep. 2022 Nov 24;7(6):e1046. doi: 10.1097/PR9.0000000000001046. eCollection 2022 Nov-Dec. Pain Rep. 2022. PMID: 36447952 Free PMC article.

3

CYP2D6-guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial.

Mosley SA, Cicali E, Del Cueto A, Portman DG, Donovan KA, Gong Y, Langaee T, Gopalan P, Schmit J, Starr JS, Silver N, Chang YD, Rajasekhara S, Smith JE, Soares HP, Clare-Salzler M, Starostik P, George TJ, McLeod HL, Fillingim RB, Hicks JK, Cavallari LH. Mosley SA, et al. Among authors: langaee t. Pharmacotherapy. 2023 Dec;43(12):1286-1296. doi: 10.1002/phar.2875. Epub 2023 Sep 21. Pharmacotherapy. 2023. PMID: 37698371 Free PMC article. Clinical Trial.

4

Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate.

Shroads AL, Langaee T, Coats BS, Kurtz TL, Bullock JR, Weithorn D, Gong Y, Wagner DA, Ostrov DA, Johnson JA, Stacpoole PW. Shroads AL, et al. Among authors: langaee t. J Clin Pharmacol. 2012 Jun;52(6):837-49. doi: 10.1177/0091270011405664. Epub 2011 Jun 3. J Clin Pharmacol. 2012. PMID: 21642471 Free PMC article.

5

Prenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetate.

Li W, Gu Y, James MO, Hines RN, Simpson P, Langaee T, Stacpoole PW. Li W, et al. Among authors: langaee t. Drug Metab Dispos. 2012 Feb;40(2):232-9. doi: 10.1124/dmd.111.041533. Epub 2011 Oct 25. Drug Metab Dispos. 2012. PMID: 22028318 Free PMC article.

6

Long-term safety of dichloroacetate in congenital lactic acidosis.

Abdelmalak M, Lew A, Ramezani R, Shroads AL, Coats BS, Langaee T, Shankar MN, Neiberger RE, Subramony SH, Stacpoole PW. Abdelmalak M, et al. Among authors: langaee t. Mol Genet Metab. 2013 Jun;109(2):139-43. doi: 10.1016/j.ymgme.2013.03.019. Epub 2013 Apr 6. Mol Genet Metab. 2013. PMID: 23611579 Free PMC article.

7

Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.

Dunbar EM, Coats BS, Shroads AL, Langaee T, Lew A, Forder JR, Shuster JJ, Wagner DA, Stacpoole PW. Dunbar EM, et al. Among authors: langaee t. Invest New Drugs. 2014 Jun;32(3):452-64. doi: 10.1007/s10637-013-0047-4. Epub 2013 Dec 3. Invest New Drugs. 2014. PMID: 24297161 Free PMC article. Clinical Trial.

8

Chloride and other anions inhibit dichloroacetate-induced inactivation of human liver GSTZ1 in a haplotype-dependent manner.

Zhong G, Li W, Gu Y, Langaee T, Stacpoole PW, James MO. Zhong G, et al. Among authors: langaee t. Chem Biol Interact. 2014 May 25;215:33-9. doi: 10.1016/j.cbi.2014.02.015. Epub 2014 Mar 13. Chem Biol Interact. 2014. PMID: 24632415 Free PMC article.

9

Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children.

Shroads AL, Coats BS, McDonough CW, Langaee T, Stacpoole PW. Shroads AL, et al. Among authors: langaee t. J Clin Pharmacol. 2015 Jan;55(1):50-5. doi: 10.1002/jcph.371. Epub 2014 Aug 6. J Clin Pharmacol. 2015. PMID: 25079374 Free PMC article. Clinical Trial.

10

Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans.

Shroads AL, Coats BS, Langaee T, Shuster JJ, Stacpoole PW. Shroads AL, et al. Among authors: langaee t. Drug Metab Pers Ther. 2015 Mar;30(1):49-55. doi: 10.1515/dmdi-2014-0015. Drug Metab Pers Ther. 2015. PMID: 25283137 Free PMC article. Clinical Trial.

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