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Page 1
Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences.
Hutchinson MR, Lewis SS, Coats BD, Rezvani N, Zhang Y, Wieseler JL, Somogyi AA, Yin H, Maier SF, Rice KC, Watkins LR. Hutchinson MR, et al. Among authors: coats bd. Neuroscience. 2010 May 19;167(3):880-93. doi: 10.1016/j.neuroscience.2010.02.011. Epub 2010 Feb 21. Neuroscience. 2010. PMID: 20178837 Free PMC article.
Evidence that opioids may have toll-like receptor 4 and MD-2 effects.
Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, Falke JJ, Leinwand LA, Maier SF, Yin H, Rice KC, Watkins LR. Hutchinson MR, et al. Among authors: coats bd. Brain Behav Immun. 2010 Jan;24(1):83-95. doi: 10.1016/j.bbi.2009.08.004. Epub 2009 Aug 11. Brain Behav Immun. 2010. PMID: 19679181 Free PMC article.
Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain.
Loram LC, Harrison JA, Sloane EM, Hutchinson MR, Sholar P, Taylor FR, Berkelhammer D, Coats BD, Poole S, Milligan ED, Maier SF, Rieger J, Watkins LR. Loram LC, et al. Among authors: coats bd. J Neurosci. 2009 Nov 4;29(44):14015-25. doi: 10.1523/JNEUROSCI.3447-09.2009. J Neurosci. 2009. PMID: 19890011 Free PMC article.
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia.
Hutchinson MR, Coats BD, Lewis SS, Zhang Y, Sprunger DB, Rezvani N, Baker EM, Jekich BM, Wieseler JL, Somogyi AA, Martin D, Poole S, Judd CM, Maier SF, Watkins LR. Hutchinson MR, et al. Among authors: coats bd. Brain Behav Immun. 2008 Nov;22(8):1178-89. doi: 10.1016/j.bbi.2008.05.004. Epub 2008 Jul 2. Brain Behav Immun. 2008. PMID: 18599265 Free PMC article.
Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy.
Sloane E, Ledeboer A, Seibert W, Coats B, van Strien M, Maier SF, Johnson KW, Chavez R, Watkins LR, Leinwand L, Milligan ED, Van Dam AM. Sloane E, et al. Brain Behav Immun. 2009 Jan;23(1):92-100. doi: 10.1016/j.bbi.2008.09.004. Epub 2008 Sep 20. Brain Behav Immun. 2009. PMID: 18835435 Free PMC article.