Tsimikas S - Search Results

1

Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein(a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein(a) transgenic mice.

Merki E, Graham MJ, Mullick AE, Miller ER, Crooke RM, Pitas RE, Witztum JL, Tsimikas S. Merki E, et al. Among authors: tsimikas s. Circulation. 2008 Aug 12;118(7):743-53. doi: 10.1161/CIRCULATIONAHA.108.786822. Epub 2008 Jul 28. Circulation. 2008. PMID: 18663084

2

Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo.

Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL. Tsimikas S, et al. J Nucl Cardiol. 1999 Jan-Feb;6(1 Pt 1):41-53. doi: 10.1016/s1071-3581(99)90064-8. J Nucl Cardiol. 1999. PMID: 10070840

3

In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression.

Tsimikas S, Shortal BP, Witztum JL, Palinski W. Tsimikas S, et al. Arterioscler Thromb Vasc Biol. 2000 Mar;20(3):689-97. doi: 10.1161/01.atv.20.3.689. Arterioscler Thromb Vasc Biol. 2000. PMID: 10712392

4

Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice.

Tsimikas S, Palinski W, Witztum JL. Tsimikas S, et al. Arterioscler Thromb Vasc Biol. 2001 Jan;21(1):95-100. doi: 10.1161/01.atv.21.1.95. Arterioscler Thromb Vasc Biol. 2001. PMID: 11145939

5

Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk.

Tsimikas S, Witztum JL. Tsimikas S, et al. Circulation. 2001 Apr 17;103(15):1930-2. doi: 10.1161/01.cir.103.15.1930. Circulation. 2001. PMID: 11306518 No abstract available.

6

Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo.

Shaw PX, Hörkkö S, Tsimikas S, Chang MK, Palinski W, Silverman GJ, Chen PP, Witztum JL. Shaw PX, et al. Among authors: tsimikas s. Arterioscler Thromb Vasc Biol. 2001 Aug;21(8):1333-9. doi: 10.1161/hq0801.093587. Arterioscler Thromb Vasc Biol. 2001. PMID: 11498462

7

Shifting the diagnosis and treatment of atherosclerosis to children and young adults: a new paradigm for the 21st century.

Tsimikas S, Witztum JL. Tsimikas S, et al. J Am Coll Cardiol. 2002 Dec 18;40(12):2122-4. doi: 10.1016/s0735-1097(02)02599-8. J Am Coll Cardiol. 2002. PMID: 12505223 Free article. No abstract available.

8

Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes.

Tsimikas S, Bergmark C, Beyer RW, Patel R, Pattison J, Miller E, Juliano J, Witztum JL. Tsimikas S, et al. J Am Coll Cardiol. 2003 Feb 5;41(3):360-70. doi: 10.1016/s0735-1097(02)02769-9. J Am Coll Cardiol. 2003. PMID: 12575961 Free article.

9

Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice.

Sukhova GK, Zhang Y, Pan JH, Wada Y, Yamamoto T, Naito M, Kodama T, Tsimikas S, Witztum JL, Lu ML, Sakara Y, Chin MT, Libby P, Shi GP. Sukhova GK, et al. Among authors: tsimikas s. J Clin Invest. 2003 Mar;111(6):897-906. doi: 10.1172/JCI14915. J Clin Invest. 2003. PMID: 12639996 Free PMC article.

10

Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a).

Edelstein C, Pfaffinger D, Hinman J, Miller E, Lipkind G, Tsimikas S, Bergmark C, Getz GS, Witztum JL, Scanu AM. Edelstein C, et al. Among authors: tsimikas s. J Biol Chem. 2003 Dec 26;278(52):52841-7. doi: 10.1074/jbc.M310425200. Epub 2003 Oct 13. J Biol Chem. 2003. PMID: 14557258 Free article.

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