Hughes SH - Search Results

1

HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision.

Delviks-Frankenberry KA, Nikolenko GN, Boyer PL, Hughes SH, Coffin JM, Jere A, Pathak VK. Delviks-Frankenberry KA, et al. Among authors: hughes sh. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10943-8. doi: 10.1073/pnas.0804660105. Epub 2008 Jul 30. Proc Natl Acad Sci U S A. 2008. PMID: 18667707 Free PMC article.

2

Mutational analysis of the fingers domain of human immunodeficiency virus type 1 reverse transcriptase.

Boyer PL, Ferris AL, Hughes SH. Boyer PL, et al. Among authors: hughes sh. J Virol. 1992 Dec;66(12):7533-7. doi: 10.1128/JVI.66.12.7533-7537.1992. J Virol. 1992. PMID: 1279205 Free PMC article.

3

Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1.

Boyer PL, Ferris AL, Hughes SH. Boyer PL, et al. Among authors: hughes sh. J Virol. 1992 Feb;66(2):1031-9. doi: 10.1128/JVI.66.2.1031-1039.1992. J Virol. 1992. PMID: 1370546 Free PMC article.

4

Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants.

Hizi A, McGill C, Hughes SH. Hizi A, et al. Among authors: hughes sh. Proc Natl Acad Sci U S A. 1988 Feb;85(4):1218-22. doi: 10.1073/pnas.85.4.1218. Proc Natl Acad Sci U S A. 1988. PMID: 2448794 Free PMC article.

5

Molecular analysis of O6-substituted guanine-induced mutagenesis of ras oncogenes.

Mitra G, Pauly GT, Kumar R, Pei GK, Hughes SH, Moschel RC, Barbacid M. Mitra G, et al. Among authors: hughes sh. Proc Natl Acad Sci U S A. 1989 Nov;86(22):8650-4. doi: 10.1073/pnas.86.22.8650. Proc Natl Acad Sci U S A. 1989. PMID: 2682655 Free PMC article.

6

Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1.

Boyer PL, Hughes SH. Boyer PL, et al. Among authors: hughes sh. Antimicrob Agents Chemother. 1995 Jul;39(7):1624-8. doi: 10.1128/AAC.39.7.1624. Antimicrob Agents Chemother. 1995. PMID: 7492119 Free PMC article.

7

Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.

Boyer PL, Tantillo C, Jacobo-Molina A, Nanni RG, Ding J, Arnold E, Hughes SH. Boyer PL, et al. Among authors: hughes sh. Proc Natl Acad Sci U S A. 1994 May 24;91(11):4882-6. doi: 10.1073/pnas.91.11.4882. Proc Natl Acad Sci U S A. 1994. PMID: 7515182 Free PMC article.

8

Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance.

Tantillo C, Ding J, Jacobo-Molina A, Nanni RG, Boyer PL, Hughes SH, Pauwels R, Andries K, Janssen PA, Arnold E. Tantillo C, et al. Among authors: hughes sh. J Mol Biol. 1994 Oct 28;243(3):369-87. doi: 10.1006/jmbi.1994.1665. J Mol Biol. 1994. PMID: 7525966 Review.

9

Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase.

Boyer PL, Ferris AL, Clark P, Whitmer J, Frank P, Tantillo C, Arnold E, Hughes SH. Boyer PL, et al. Among authors: hughes sh. J Mol Biol. 1994 Oct 28;243(3):472-83. doi: 10.1006/jmbi.1994.1673. J Mol Biol. 1994. PMID: 7525967

10

Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase.

Boyer PL, Ding J, Arnold E, Hughes SH. Boyer PL, et al. Among authors: hughes sh. Antimicrob Agents Chemother. 1994 Sep;38(9):1909-14. doi: 10.1128/AAC.38.9.1909. Antimicrob Agents Chemother. 1994. PMID: 7529011 Free PMC article.

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