Kalvinsh I - Search Results

1

Novel amide derivatives as inhibitors of histone deacetylase: design, synthesis and SAR.

Andrianov V, Gailite V, Lola D, Loza E, Semenikhina V, Kalvinsh I, Finn P, Petersen KD, Ritchie JW, Khan N, Tumber A, Collins LS, Vadlamudi SM, Björkling F, Sehested M. Andrianov V, et al. Among authors: kalvinsh i. Eur J Med Chem. 2009 Mar;44(3):1067-85. doi: 10.1016/j.ejmech.2008.06.020. Epub 2008 Jun 27. Eur J Med Chem. 2009. PMID: 18672316

2

Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones.

Christensen MK, Erichsen KD, Trojel-Hansen C, Tjørnelund J, Nielsen SJ, Frydenvang K, Johansen TN, Nielsen B, Sehested M, Jensen PB, Ikaunieks M, Zaichenko A, Loza E, Kalvinsh I, Björkling F. Christensen MK, et al. Among authors: kalvinsh i. J Med Chem. 2010 Oct 14;53(19):7140-5. doi: 10.1021/jm100763j. J Med Chem. 2010. PMID: 20845961

3

Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei.

Kelly JM, Taylor MC, Horn D, Loza E, Kalvinsh I, Björkling F. Kelly JM, et al. Among authors: kalvinsh i. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1886-90. doi: 10.1016/j.bmcl.2012.01.072. Epub 2012 Jan 28. Bioorg Med Chem Lett. 2012. PMID: 22326398 Free PMC article.

4

Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship.

Christensen MK, Erichsen KD, Olesen UH, Tjørnelund J, Fristrup P, Thougaard A, Nielsen SJ, Sehested M, Jensen PB, Loza E, Kalvinsh I, Garten A, Kiess W, Björkling F. Christensen MK, et al. Among authors: kalvinsh i. J Med Chem. 2013 Nov 27;56(22):9071-88. doi: 10.1021/jm4009949. Epub 2013 Nov 13. J Med Chem. 2013. PMID: 24164086

5

Targeting carnitine biosynthesis: discovery of new inhibitors against γ-butyrobetaine hydroxylase.

Tars K, Leitans J, Kazaks A, Zelencova D, Liepinsh E, Kuka J, Makrecka M, Lola D, Andrianovs V, Gustina D, Grinberga S, Liepinsh E, Kalvinsh I, Dambrova M, Loza E, Pugovics O. Tars K, et al. Among authors: kalvinsh i. J Med Chem. 2014 Mar 27;57(6):2213-36. doi: 10.1021/jm401603e. Epub 2014 Mar 14. J Med Chem. 2014. PMID: 24571165

6

Synthesis and quantitative structure-activity relationship of hydrazones of N-amino-N'-hydroxyguanidine as electron acceptors for xanthine oxidase.

Prusis P, Dambrova M, Andrianov V, Rozhkov E, Semenikhina V, Piskunova I, Ongwae E, Lundstedt T, Kalvinsh I, Wikberg JE. Prusis P, et al. Among authors: kalvinsh i. J Med Chem. 2004 Jun 3;47(12):3105-10. doi: 10.1021/jm031127c. J Med Chem. 2004. PMID: 15163191

7

Paradoxical effects of two oximes on nitric oxide production by purified NO synthases, in cell culture and in animals.

Sjakste N, Andrianov VG, Boucher JL, Shestakova I, Baumane L, Dzintare M, Meirena D, Kalvinsh I. Sjakste N, et al. Among authors: kalvinsh i. Nitric Oxide. 2007 Nov-Dec;17(3-4):107-14. doi: 10.1016/j.niox.2007.06.007. Epub 2007 Jul 12. Nitric Oxide. 2007. PMID: 17702619

8

Synthesis and antitumor activity of selected 7-alkylidene substituted cephems.

Veinberg G, Vorona M, Shestakova I, Kanepe I, Zharkova O, Mezapuke R, Turovskis I, Kalvinsh I, Lukevics E. Veinberg G, et al. Among authors: kalvinsh i. Bioorg Med Chem. 2000 May;8(5):1033-40. doi: 10.1016/s0968-0896(00)00035-3. Bioorg Med Chem. 2000. PMID: 10882015

9

Synthesis and structure-affinity relationships of 1,3, 5-alkylsubstituted cyclohexylamines binding at NMDA receptor PCP site.

Jirgensons A, Kauss V, Kalvinsh I, Gold MR, Danysz W, Parsons CG, Quack G. Jirgensons A, et al. Among authors: kalvinsh i. Eur J Med Chem. 2000 Jun;35(6):555-65. doi: 10.1016/s0223-5234(00)00153-7. Eur J Med Chem. 2000. PMID: 10906408

10

Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism.

Jaudzems K, Kuka J, Gutsaits A, Zinovjevs K, Kalvinsh I, Liepinsh E, Liepinsh E, Dambrova M. Jaudzems K, et al. Among authors: kalvinsh i. J Enzyme Inhib Med Chem. 2009 Dec;24(6):1269-75. doi: 10.3109/14756360902829527. J Enzyme Inhib Med Chem. 2009. PMID: 19912061 Free article.

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