Frezza C - Search Results

1

A novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in function.

Spinazzi M, Cazzola S, Bortolozzi M, Baracca A, Loro E, Casarin A, Solaini G, Sgarbi G, Casalena G, Cenacchi G, Malena A, Frezza C, Carrara F, Angelini C, Scorrano L, Salviati L, Vergani L. Spinazzi M, et al. Among authors: frezza c. Hum Mol Genet. 2008 Nov 1;17(21):3291-302. doi: 10.1093/hmg/ddn225. Epub 2008 Aug 4. Hum Mol Genet. 2008. PMID: 18678599

2

Measuring mitochondrial shape changes and their consequences on mitochondrial involvement during apoptosis.

Frezza C, Cipolat S, Scorrano L. Frezza C, et al. Methods Mol Biol. 2007;372:405-20. doi: 10.1007/978-1-59745-365-3_29. Methods Mol Biol. 2007. PMID: 18314742

3

Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts.

Frezza C, Cipolat S, Scorrano L. Frezza C, et al. Nat Protoc. 2007;2(2):287-95. doi: 10.1038/nprot.2006.478. Nat Protoc. 2007. PMID: 17406588

4

Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.

Cipolat S, Rudka T, Hartmann D, Costa V, Serneels L, Craessaerts K, Metzger K, Frezza C, Annaert W, D'Adamio L, Derks C, Dejaegere T, Pellegrini L, D'Hooge R, Scorrano L, De Strooper B. Cipolat S, et al. Among authors: frezza c. Cell. 2006 Jul 14;126(1):163-75. doi: 10.1016/j.cell.2006.06.021. Cell. 2006. PMID: 16839884 Free article.

5

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion.

Frezza C, Cipolat S, Martins de Brito O, Micaroni M, Beznoussenko GV, Rudka T, Bartoli D, Polishuck RS, Danial NN, De Strooper B, Scorrano L. Frezza C, et al. Cell. 2006 Jul 14;126(1):177-89. doi: 10.1016/j.cell.2006.06.025. Cell. 2006. PMID: 16839885 Free article.

6

Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency.

Cogliati S, Frezza C, Soriano ME, Varanita T, Quintana-Cabrera R, Corrado M, Cipolat S, Costa V, Casarin A, Gomes LC, Perales-Clemente E, Salviati L, Fernandez-Silva P, Enriquez JA, Scorrano L. Cogliati S, et al. Among authors: frezza c. Cell. 2013 Sep 26;155(1):160-71. doi: 10.1016/j.cell.2013.08.032. Epub 2013 Sep 19. Cell. 2013. PMID: 24055366 Free PMC article.

7

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.

Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D, Van Coster R, Wurst W, Scorrano L, De Strooper B. Morais VA, et al. Among authors: frezza c. EMBO Mol Med. 2009 May;1(2):99-111. doi: 10.1002/emmm.200900006. EMBO Mol Med. 2009. PMID: 20049710 Free PMC article.

8

4-hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one induces mitochondrial dysfunction and apoptosis upon its intracellular oxidation.

Chilin A, Dodoni G, Frezza C, Guiotto A, Barbieri V, Di Lisa F, Canton M. Chilin A, et al. Among authors: frezza c. J Med Chem. 2005 Jan 13;48(1):192-9. doi: 10.1021/jm0493919. J Med Chem. 2005. PMID: 15634013

9

Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects.

Tyrakis PA, Yurkovich ME, Sciacovelli M, Papachristou EK, Bridges HR, Gaude E, Schreiner A, D'Santos C, Hirst J, Hernandez-Fernaud J, Springett R, Griffiths JR, Frezza C. Tyrakis PA, et al. Among authors: frezza c. Cell Rep. 2017 Oct 24;21(4):1036-1047. doi: 10.1016/j.celrep.2017.09.092. Cell Rep. 2017. PMID: 29069586 Free PMC article.

10

The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase.

Sciacovelli M, Guzzo G, Morello V, Frezza C, Zheng L, Nannini N, Calabrese F, Laudiero G, Esposito F, Landriscina M, Defilippi P, Bernardi P, Rasola A. Sciacovelli M, et al. Among authors: frezza c. Cell Metab. 2013 Jun 4;17(6):988-999. doi: 10.1016/j.cmet.2013.04.019. Cell Metab. 2013. PMID: 23747254 Free PMC article.

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