Bettayeb K - Search Results

1

Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.

Oumata N, Bettayeb K, Ferandin Y, Demange L, Lopez-Giral A, Goddard ML, Myrianthopoulos V, Mikros E, Flajolet M, Greengard P, Meijer L, Galons H. Oumata N, et al. Among authors: bettayeb k. J Med Chem. 2008 Sep 11;51(17):5229-42. doi: 10.1021/jm800109e. Epub 2008 Aug 13. J Med Chem. 2008. PMID: 18698753

2

Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.

Popowycz F, Fournet G, Schneider C, Bettayeb K, Ferandin Y, Lamigeon C, Tirado OM, Mateo-Lozano S, Notario V, Colas P, Bernard P, Meijer L, Joseph B. Popowycz F, et al. Among authors: bettayeb k. J Med Chem. 2009 Feb 12;52(3):655-63. doi: 10.1021/jm801340z. J Med Chem. 2009. PMID: 19128055 Free PMC article.

3

Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors.

N'gompaza-Diarra J, Bettayeb K, Gresh N, Meijer L, Oumata N. N'gompaza-Diarra J, et al. Among authors: bettayeb k. Eur J Med Chem. 2012 Oct;56:210-6. doi: 10.1016/j.ejmech.2012.08.033. Epub 2012 Sep 1. Eur J Med Chem. 2012. PMID: 22982525

4

CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases.

Bettayeb K, Oumata N, Echalier A, Ferandin Y, Endicott JA, Galons H, Meijer L. Bettayeb K, et al. Oncogene. 2008 Oct 2;27(44):5797-807. doi: 10.1038/onc.2008.191. Epub 2008 Jun 23. Oncogene. 2008. PMID: 18574471

5

3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.

Ferandin Y, Bettayeb K, Kritsanida M, Lozach O, Polychronopoulos P, Magiatis P, Skaltsounis AL, Meijer L. Ferandin Y, et al. Among authors: bettayeb k. J Med Chem. 2006 Jul 27;49(15):4638-49. doi: 10.1021/jm060314i. J Med Chem. 2006. PMID: 16854069

6

Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.

Echalier A, Bettayeb K, Ferandin Y, Lozach O, Clément M, Valette A, Liger F, Marquet B, Morris JC, Endicott JA, Joseph B, Meijer L. Echalier A, et al. Among authors: bettayeb k. J Med Chem. 2008 Feb 28;51(4):737-51. doi: 10.1021/jm700940h. Epub 2008 Jan 31. J Med Chem. 2008. PMID: 18232649

The crystal structures of 1e (meriolin 5) and variolin B (Bettayeb, K.; Tirado, O. M.; Marionneau-Lambert, S.; Ferandin, Y.; Lozach, O.; Morris, J.; Mateo-Lozano, S.; Druckes, P.; Schachtele, C.; Kubbutat, M.; Liger, F.; Marquet, B.; Joseph, B.; Echalier, A.; Endico …

The crystal structures of 1e (meriolin 5) and variolin B (Bettayeb, K.; Tirado, O. M.; Marionneau-Lambert, S.; Ferandin, Y.; L …

7

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine.

Bettayeb K, Sallam H, Ferandin Y, Popowycz F, Fournet G, Hassan M, Echalier A, Bernard P, Endicott J, Joseph B, Meijer L. Bettayeb K, et al. Mol Cancer Ther. 2008 Sep;7(9):2713-24. doi: 10.1158/1535-7163.MCT-08-0080. Mol Cancer Ther. 2008. PMID: 18790752 Free article.

8

Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period.

Vougogiannopoulou K, Ferandin Y, Bettayeb K, Myrianthopoulos V, Lozach O, Fan Y, Johnson CH, Magiatis P, Skaltsounis AL, Mikros E, Meijer L. Vougogiannopoulou K, et al. Among authors: bettayeb k. J Med Chem. 2008 Oct 23;51(20):6421-31. doi: 10.1021/jm800648y. Epub 2008 Sep 25. J Med Chem. 2008. PMID: 18816110 Free PMC article.

9

Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases.

Bettayeb K, Tirado OM, Marionneau-Lambot S, Ferandin Y, Lozach O, Morris JC, Mateo-Lozano S, Drueckes P, Schächtele C, Kubbutat MH, Liger F, Marquet B, Joseph B, Echalier A, Endicott JA, Notario V, Meijer L. Bettayeb K, et al. Cancer Res. 2007 Sep 1;67(17):8325-34. doi: 10.1158/0008-5472.CAN-07-1826. Cancer Res. 2007. PMID: 17804748

10

Aftins increase amyloid-β42, lower amyloid-β38, and do not alter amyloid-β40 extracellular production in vitro: toward a chemical model of Alzheimer's disease?

Hochard A, Oumata N, Bettayeb K, Gloulou O, Fant X, Durieu E, Buron N, Porceddu M, Borgne-Sanchez A, Galons H, Flajolet M, Meijer L. Hochard A, et al. Among authors: bettayeb k. J Alzheimers Dis. 2013;35(1):107-20. doi: 10.3233/JAD-121777. J Alzheimers Dis. 2013. PMID: 23364140 Free PMC article.

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