Flajolet M - Search Results

1

Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.

Oumata N, Bettayeb K, Ferandin Y, Demange L, Lopez-Giral A, Goddard ML, Myrianthopoulos V, Mikros E, Flajolet M, Greengard P, Meijer L, Galons H. Oumata N, et al. Among authors: flajolet m. J Med Chem. 2008 Sep 11;51(17):5229-42. doi: 10.1021/jm800109e. Epub 2008 Aug 13. J Med Chem. 2008. PMID: 18698753

2

Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3.

Flajolet M, Rakhilin S, Wang H, Starkova N, Nuangchamnong N, Nairn AC, Greengard P. Flajolet M, et al. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):16006-11. doi: 10.1073/pnas.2136600100. Epub 2003 Dec 8. Proc Natl Acad Sci U S A. 2003. PMID: 14663150 Free PMC article.

3

Pharmacological inhibitors of glycogen synthase kinase 3.

Meijer L, Flajolet M, Greengard P. Meijer L, et al. Among authors: flajolet m. Trends Pharmacol Sci. 2004 Sep;25(9):471-80. doi: 10.1016/j.tips.2004.07.006. Trends Pharmacol Sci. 2004. PMID: 15559249 Review.

4

Discovery of protein phosphatase 2C inhibitors by virtual screening.

Rogers JP, Beuscher AE 4th, Flajolet M, McAvoy T, Nairn AC, Olson AJ, Greengard P. Rogers JP, et al. Among authors: flajolet m. J Med Chem. 2006 Mar 9;49(5):1658-67. doi: 10.1021/jm051033y. J Med Chem. 2006. PMID: 16509582 Free PMC article.

5

Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I.

Flajolet M, He G, Heiman M, Lin A, Nairn AC, Greengard P. Flajolet M, et al. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4159-64. doi: 10.1073/pnas.0611236104. Epub 2007 Feb 27. Proc Natl Acad Sci U S A. 2007. PMID: 17360493 Free PMC article.

6

FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity.

Flajolet M, Wang Z, Futter M, Shen W, Nuangchamnong N, Bendor J, Wallach I, Nairn AC, Surmeier DJ, Greengard P. Flajolet M, et al. Nat Neurosci. 2008 Dec;11(12):1402-9. doi: 10.1038/nn.2216. Epub 2008 Oct 26. Nat Neurosci. 2008. PMID: 18953346 Free PMC article.

7

CK2 negatively regulates Galphas signaling.

Rebholz H, Nishi A, Liebscher S, Nairn AC, Flajolet M, Greengard P. Rebholz H, et al. Among authors: flajolet m. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14096-101. doi: 10.1073/pnas.0906857106. Epub 2009 Aug 3. Proc Natl Acad Sci U S A. 2009. PMID: 19666609 Free PMC article.

8

Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model.

Netzer WJ, Powell C, Nong Y, Blundell J, Wong L, Duff K, Flajolet M, Greengard P. Netzer WJ, et al. Among authors: flajolet m. PLoS One. 2010 Jun 3;5(6):e10943. doi: 10.1371/journal.pone.0010943. PLoS One. 2010. PMID: 20532168 Free PMC article.

9

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.

He G, Luo W, Li P, Remmers C, Netzer WJ, Hendrick J, Bettayeb K, Flajolet M, Gorelick F, Wennogle LP, Greengard P. He G, et al. Among authors: flajolet m. Nature. 2010 Sep 2;467(7311):95-8. doi: 10.1038/nature09325. Nature. 2010. PMID: 20811458 Free PMC article.

10

[mGluR5: a receptor at the therapeutic crossroad?].

Flajolet M, Wang H, Greengard P. Flajolet M, et al. Med Sci (Paris). 2010 Aug-Sep;26(8-9):678-80. doi: 10.1051/medsci/2010268-9678. Med Sci (Paris). 2010. PMID: 20819696 Free article. French. No abstract available.

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