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Page 1
Discovery of protein phosphatase 2C inhibitors by virtual screening.
Rogers JP, Beuscher AE 4th, Flajolet M, McAvoy T, Nairn AC, Olson AJ, Greengard P. Rogers JP, et al. Among authors: greengard p. J Med Chem. 2006 Mar 9;49(5):1658-67. doi: 10.1021/jm051033y. J Med Chem. 2006. PMID: 16509582 Free PMC article.
Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I.
Flajolet M, He G, Heiman M, Lin A, Nairn AC, Greengard P. Flajolet M, et al. Among authors: greengard p. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4159-64. doi: 10.1073/pnas.0611236104. Epub 2007 Feb 27. Proc Natl Acad Sci U S A. 2007. PMID: 17360493 Free PMC article.
Pharmacological inhibitors of cyclin-dependent kinases.
Knockaert M, Greengard P, Meijer L. Knockaert M, et al. Among authors: greengard p. Trends Pharmacol Sci. 2002 Sep;23(9):417-25. doi: 10.1016/s0165-6147(02)02071-0. Trends Pharmacol Sci. 2002. PMID: 12237154 Review.
Pharmacological inhibitors of glycogen synthase kinase 3.
Meijer L, Flajolet M, Greengard P. Meijer L, et al. Among authors: greengard p. Trends Pharmacol Sci. 2004 Sep;25(9):471-80. doi: 10.1016/j.tips.2004.07.006. Trends Pharmacol Sci. 2004. PMID: 15559249 Review.
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?
Leclerc S, Garnier M, Hoessel R, Marko D, Bibb JA, Snyder GL, Greengard P, Biernat J, Wu YZ, Mandelkow EM, Eisenbrand G, Meijer L. Leclerc S, et al. Among authors: greengard p. J Biol Chem. 2001 Jan 5;276(1):251-60. doi: 10.1074/jbc.M002466200. J Biol Chem. 2001. PMID: 11013232 Free article.
GSK-3-selective inhibitors derived from Tyrian purple indirubins.
Meijer L, Skaltsounis AL, Magiatis P, Polychronopoulos P, Knockaert M, Leost M, Ryan XP, Vonica CA, Brivanlou A, Dajani R, Crovace C, Tarricone C, Musacchio A, Roe SM, Pearl L, Greengard P. Meijer L, et al. Among authors: greengard p. Chem Biol. 2003 Dec;10(12):1255-66. doi: 10.1016/j.chembiol.2003.11.010. Chem Biol. 2003. PMID: 14700633
950 results