Bognar A - Search Results

1

A domino effect in antifolate drug action in Escherichia coli.

Kwon YK, Lu W, Melamud E, Khanam N, Bognar A, Rabinowitz JD. Kwon YK, et al. Among authors: bognar a. Nat Chem Biol. 2008 Oct;4(10):602-8. doi: 10.1038/nchembio.108. Epub 2008 Aug 24. Nat Chem Biol. 2008. PMID: 18724364 Free PMC article.

2

Mutagenesis of folylpolyglutamate synthetase indicates that dihydropteroate and tetrahydrofolate bind to the same site.

Sheng Y, Khanam N, Tsaksis Y, Shi XM, Lu QS, Bognar AL. Sheng Y, et al. Biochemistry. 2008 Feb 26;47(8):2388-96. doi: 10.1021/bi701670y. Epub 2008 Jan 31. Biochemistry. 2008. PMID: 18232714

3

Transcriptional regulation of the one-carbon metabolism regulon in Saccharomyces cerevisiae by Bas1p.

Subramanian M, Qiao WB, Khanam N, Wilkins O, Der SD, Lalich JD, Bognar AL. Subramanian M, et al. Mol Microbiol. 2005 Jul;57(1):53-69. doi: 10.1111/j.1365-2958.2005.04663.x. Mol Microbiol. 2005. PMID: 15948949 Free article.

4

Primary structure of the Escherichia coli folC gene and its folylpolyglutamate synthetase-dihydrofolate synthetase product and regulation of expression by an upstream gene.

Bognar AL, Osborne C, Shane B. Bognar AL, et al. J Biol Chem. 1987 Sep 5;262(25):12337-43. J Biol Chem. 1987. PMID: 3040739 Free article.

5

Purification and crystallization of Lactobacillus casei folylpolyglutamate synthetase expressed in Escherichia coli.

Cody V, Luft JR, Pangborn W, Toy J, Bognar AL. Cody V, et al. Among authors: bognar al. J Mol Biol. 1992 Apr 20;224(4):1179-80. doi: 10.1016/0022-2836(92)90480-8. J Mol Biol. 1992. PMID: 1569575

6

Replacement of the folC gene, encoding folylpolyglutamate synthetase-dihydrofolate synthetase in Escherichia coli, with genes mutagenized in vitro.

Pyne C, Bognar AL. Pyne C, et al. Among authors: bognar al. J Bacteriol. 1992 Mar;174(6):1750-9. doi: 10.1128/jb.174.6.1750-1759.1992. J Bacteriol. 1992. PMID: 1548226 Free PMC article.

7

Characterization of a mutation affecting the function of Escherichia coli folylpolyglutamate synthetase-dihydrofolate synthetase and further mutations produced in vitro at the same locus.

Keshavjee K, Pyne C, Bognar AL. Keshavjee K, et al. Among authors: bognar al. J Biol Chem. 1991 Oct 25;266(30):19925-9. J Biol Chem. 1991. PMID: 1939056 Free article.

8

Mutation of an essential glutamate residue in folylpolyglutamate synthetase and activation of the enzyme by pteroate binding.

Sheng Y, Cross JA, Shen Y, Smith CA, Bognar AL. Sheng Y, et al. Among authors: bognar al. Arch Biochem Biophys. 2002 Jun 1;402(1):94-103. doi: 10.1016/S0003-9861(02)00040-1. Arch Biochem Biophys. 2002. PMID: 12051687

9

Binding of ATP as well as tetrahydrofolate induces conformational changes in Lactobacillus casei folylpolyglutamate synthetase in solution.

Sheng Y, Ip H, Liu J, Davidson A, Bognar AL. Sheng Y, et al. Among authors: bognar al. Biochemistry. 2003 Feb 18;42(6):1537-43. doi: 10.1021/bi027024y. Biochemistry. 2003. PMID: 12578366

10

Structural and functional similarities in the ADP-forming amide bond ligase superfamily: implications for a substrate-induced conformational change in folylpolyglutamate synthetase.

Sheng Y, Sun X, Shen Y, Bognar AL, Baker EN, Smith CA. Sheng Y, et al. Among authors: bognar al. J Mol Biol. 2000 Sep 15;302(2):427-40. doi: 10.1006/jmbi.2000.3987. J Mol Biol. 2000. PMID: 10970743

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