Edwards MD - Search Results

1

The structure of an open form of an E. coli mechanosensitive channel at 3.45 A resolution.

Wang W, Black SS, Edwards MD, Miller S, Morrison EL, Bartlett W, Dong C, Naismith JH, Booth IR. Wang W, et al. Among authors: edwards md. Science. 2008 Aug 29;321(5893):1179-83. doi: 10.1126/science.1159262. Science. 2008. PMID: 18755969 Free PMC article.

2

Gating the bacterial mechanosensitive channels: MscS a new paradigm?

Edwards MD, Booth IR, Miller S. Edwards MD, et al. Curr Opin Microbiol. 2004 Apr;7(2):163-7. doi: 10.1016/j.mib.2004.02.006. Curr Opin Microbiol. 2004. PMID: 15063854 Review.

3

Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel.

Edwards MD, Li Y, Kim S, Miller S, Bartlett W, Black S, Dennison S, Iscla I, Blount P, Bowie JU, Booth IR. Edwards MD, et al. Nat Struct Mol Biol. 2005 Feb;12(2):113-9. doi: 10.1038/nsmb895. Epub 2005 Jan 23. Nat Struct Mol Biol. 2005. PMID: 15665866

4

Identification of mutations that alter the gating of the Escherichia coli mechanosensitive channel protein, MscK.

Li C, Edwards MD, Jeong H, Roth J, Booth IR. Li C, et al. Among authors: edwards md. Mol Microbiol. 2007 Apr;64(2):560-74. doi: 10.1111/j.1365-2958.2007.05672.x. Mol Microbiol. 2007. PMID: 17493135 Free PMC article.

5

The role of tryptophan residues in the function and stability of the mechanosensitive channel MscS from Escherichia coli.

Rasmussen A, Rasmussen T, Edwards MD, Schauer D, Schumann U, Miller S, Booth IR. Rasmussen A, et al. Among authors: edwards md. Biochemistry. 2007 Sep 25;46(38):10899-908. doi: 10.1021/bi701056k. Epub 2007 Aug 24. Biochemistry. 2007. PMID: 17718516

6

Pore mutations of the Escherichia coli MscS channel affect desensitization but not ionic preference.

Edwards MD, Bartlett W, Booth IR. Edwards MD, et al. Biophys J. 2008 Apr 15;94(8):3003-13. doi: 10.1529/biophysj.107.123448. Epub 2007 Dec 7. Biophys J. 2008. PMID: 18065458 Free PMC article.

7

Tryptophan in the pore of the mechanosensitive channel MscS: assessment of pore conformations by fluorescence spectroscopy.

Rasmussen T, Edwards MD, Black SS, Rasmussen A, Miller S, Booth IR. Rasmussen T, et al. Among authors: edwards md. J Biol Chem. 2010 Feb 19;285(8):5377-84. doi: 10.1074/jbc.M109.071472. Epub 2009 Dec 26. J Biol Chem. 2010. PMID: 20037156 Free PMC article.

8

Sensing bilayer tension: bacterial mechanosensitive channels and their gating mechanisms.

Booth IR, Rasmussen T, Edwards MD, Black S, Rasmussen A, Bartlett W, Miller S. Booth IR, et al. Among authors: edwards md. Biochem Soc Trans. 2011 Jun;39(3):733-40. doi: 10.1042/BST0390733. Biochem Soc Trans. 2011. PMID: 21599642

9

Characterization of three novel mechanosensitive channel activities in Escherichia coli.

Edwards MD, Black S, Rasmussen T, Rasmussen A, Stokes NR, Stephen TL, Miller S, Booth IR. Edwards MD, et al. Channels (Austin). 2012 Jul-Aug;6(4):272-81. doi: 10.4161/chan.20998. Epub 2012 Jul 1. Channels (Austin). 2012. PMID: 22874652 Free PMC article.

10

Domain organization of the MscS mechanosensitive channel of Escherichia coli.

Miller S, Bartlett W, Chandrasekaran S, Simpson S, Edwards M, Booth IR. Miller S, et al. EMBO J. 2003 Jan 2;22(1):36-46. doi: 10.1093/emboj/cdg011. EMBO J. 2003. PMID: 12505982 Free PMC article.

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