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ID4 regulates mammary gland development by suppressing p38MAPK activity.
Dong J, Huang S, Caikovski M, Ji S, McGrath A, Custorio MG, Creighton CJ, Maliakkal P, Bogoslovskaia E, Du Z, Zhang X, Lewis MT, Sablitzky F, Brisken C, Li Y. Dong J, et al. Among authors: li y. Development. 2011 Dec;138(23):5247-56. doi: 10.1242/dev.069203. Development. 2011. PMID: 22069192 Free PMC article.
LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.
Yue Z, Yuan Z, Zeng L, Wang Y, Lai L, Li J, Sun P, Xue X, Qi J, Yang Z, Zheng Y, Fang Y, Li D, Siwko S, Li Y, Luo J, Liu M. Yue Z, et al. Among authors: li d, li y, li j. FASEB J. 2018 May;32(5):2422-2437. doi: 10.1096/fj.201700897R. Epub 2017 Dec 21. FASEB J. 2018. PMID: 29269400 Free PMC article.
Our findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast CSCs.-Yue, Z., Yuan, Z., Zeng, L., Wang, Y., Lai, L., Li, J., Sun, P., Xue, X., Qi, J., Yang, Z., Zheng, Y., Fang, Y., Li
Our findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast CSCs.-Yue, Z., Y …
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