Crooks PA - Search Results

1

bis-Pyridinium cyclophanes: novel ligands with high affinity for the blood-brain barrier choline transporter.

Zhang Z, Lockman PR, Mittapalli RK, Allen DD, Dwoskin LP, Crooks PA. Zhang Z, et al. Among authors: crooks pa. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5622-5. doi: 10.1016/j.bmcl.2008.08.099. Epub 2008 Aug 30. Bioorg Med Chem Lett. 2008. PMID: 18793853 Free PMC article.

2

bis-Azaaromatic quaternary ammonium analogues: ligands for alpha4beta2* and alpha7* subtypes of neuronal nicotinic receptors.

Ayers JT, Dwoskin LP, Deaciuc AG, Grinevich VP, Zhu J, Crooks PA. Ayers JT, et al. Among authors: crooks pa. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3067-71. doi: 10.1016/s0960-894x(02)00687-x. Bioorg Med Chem Lett. 2002. PMID: 12372503

3

Active transport of high-affinity choline and nicotine analogs into the central nervous system by the blood-brain barrier choline transporter.

Allen DD, Lockman PR, Roder KE, Dwoskin LP, Crooks PA. Allen DD, et al. Among authors: crooks pa. J Pharmacol Exp Ther. 2003 Mar;304(3):1268-74. doi: 10.1124/jpet.102.045856. J Pharmacol Exp Ther. 2003. PMID: 12604705

4

Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.

Crooks PA, Ayers JT, Xu R, Sumithran SP, Grinevich VP, Wilkins LH, Deaciuc AG, Allen DD, Dwoskin LP. Crooks PA, et al. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1869-74. doi: 10.1016/j.bmcl.2003.10.074. Bioorg Med Chem Lett. 2004. PMID: 15050618

5

3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the blood-brain barrier choline transporter.

Geldenhuys WJ, Lockman PR, Nguyen TH, Van der Schyf CJ, Crooks PA, Dwoskin LP, Allen DD. Geldenhuys WJ, et al. Among authors: crooks pa. Bioorg Med Chem. 2005 Jul 1;13(13):4253-61. doi: 10.1016/j.bmc.2005.04.020. Bioorg Med Chem. 2005. PMID: 15878282

6

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2.

Zheng G, Dwoskin LP, Deaciuc AG, Zhu J, Jones MD, Crooks PA. Zheng G, et al. Among authors: crooks pa. Bioorg Med Chem. 2005 Jun 2;13(12):3899-909. doi: 10.1016/j.bmc.2005.04.013. Bioorg Med Chem. 2005. PMID: 15911306 Free PMC article.

7

Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.

Zheng G, Dwoskin LP, Deaciuc AG, Norrholm SD, Crooks PA. Zheng G, et al. Among authors: crooks pa. J Med Chem. 2005 Aug 25;48(17):5551-60. doi: 10.1021/jm0501228. J Med Chem. 2005. PMID: 16107155 Free PMC article.

8

Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands.

Zheng G, Dwoskin LP, Deaciuc AG, Crooks PA. Zheng G, et al. Among authors: crooks pa. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4463-6. doi: 10.1016/j.bmcl.2005.07.032. Bioorg Med Chem Lett. 2005. PMID: 16112864 Free PMC article.

9

Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the alpha4beta2 nicotinic acetylcholine receptor subtype using nonlinear techniques.

Ayers JT, Clauset A, Schmitt JD, Dwoskin LP, Crooks PA. Ayers JT, et al. Among authors: crooks pa. AAPS J. 2005 Oct 25;7(3):E678-85. doi: 10.1208/aapsj070368. AAPS J. 2005. PMID: 16353944 Free PMC article.

10

QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release.

Zheng F, Bayram E, Sumithran SP, Ayers JT, Zhan CG, Schmitt JD, Dwoskin LP, Crooks PA. Zheng F, et al. Among authors: crooks pa. Bioorg Med Chem. 2006 May 1;14(9):3017-37. doi: 10.1016/j.bmc.2005.12.036. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431111

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