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N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.
Dwoskin LP, Wooters TE, Sumithran SP, Siripurapu KB, Joyce BM, Lockman PR, Manda VK, Ayers JT, Zhang Z, Deaciuc AG, McIntosh JM, Crooks PA, Bardo MT. Dwoskin LP, et al. Among authors: zhang z. J Pharmacol Exp Ther. 2008 Aug;326(2):563-76. doi: 10.1124/jpet.108.136630. Epub 2008 May 6. J Pharmacol Exp Ther. 2008. PMID: 18460644 Free PMC article.
Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.
Zheng G, Zhang Z, Dowell C, Wala E, Dwoskin LP, Holtman JR, McIntosh JM, Crooks PA. Zheng G, et al. Among authors: zhang z. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2476-9. doi: 10.1016/j.bmcl.2011.02.043. Epub 2011 Feb 23. Bioorg Med Chem Lett. 2011. PMID: 21397497 Free PMC article.
The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens.
Rahman S, Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT. Rahman S, et al. Among authors: zhang z. Neuropharmacology. 2007 Mar;52(3):755-63. doi: 10.1016/j.neuropharm.2006.09.012. Epub 2006 Nov 9. Neuropharmacology. 2007. PMID: 17097117
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