Simon MD - Search Results

1

The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure.

Lu X, Simon MD, Chodaparambil JV, Hansen JC, Shokat KM, Luger K. Lu X, et al. Among authors: simon md. Nat Struct Mol Biol. 2008 Oct;15(10):1122-4. doi: 10.1038/nsmb.1489. Epub 2008 Sep 14. Nat Struct Mol Biol. 2008. PMID: 18794842 Free PMC article.

2

Adaptability at a protein-DNA interface: re-engineering the engrailed homeodomain to recognize an unnatural nucleotide.

Simon MD, Shokat KM. Simon MD, et al. J Am Chem Soc. 2004 Jul 7;126(26):8078-9. doi: 10.1021/ja048113w. J Am Chem Soc. 2004. PMID: 15225024

3

A phage display selection of engrailed homeodomain mutants and the importance of residue Q50.

Simon MD, Sato K, Weiss GA, Shokat KM. Simon MD, et al. Nucleic Acids Res. 2004 Jul 9;32(12):3623-31. doi: 10.1093/nar/gkh690. Print 2004. Nucleic Acids Res. 2004. PMID: 15247345 Free PMC article.

4

Dissecting the Engrailed homeodomain-DNA interaction by phage-displayed shotgun scanning.

Sato K, Simon MD, Levin AM, Shokat KM, Weiss GA. Sato K, et al. Among authors: simon md. Chem Biol. 2004 Jul;11(7):1017-23. doi: 10.1016/j.chembiol.2004.05.008. Chem Biol. 2004. PMID: 15271360 Free article.

5

Structure and properties of a re-engineered homeodomain protein-DNA interface.

Simon MD, Feldman ME, Rauh D, Maris AE, Wemmer DE, Shokat KM. Simon MD, et al. ACS Chem Biol. 2006 Dec 15;1(12):755-60. doi: 10.1021/cb6003756. ACS Chem Biol. 2006. PMID: 17240973

6

The site-specific installation of methyl-lysine analogs into recombinant histones.

Simon MD, Chu F, Racki LR, de la Cruz CC, Burlingame AL, Panning B, Narlikar GJ, Shokat KM. Simon MD, et al. Cell. 2007 Mar 9;128(5):1003-12. doi: 10.1016/j.cell.2006.12.041. Cell. 2007. PMID: 17350582 Free PMC article.

7

ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.

Hung T, Binda O, Champagne KS, Kuo AJ, Johnson K, Chang HY, Simon MD, Kutateladze TG, Gozani O. Hung T, et al. Among authors: simon md. Mol Cell. 2009 Jan 30;33(2):248-56. doi: 10.1016/j.molcel.2008.12.016. Mol Cell. 2009. PMID: 19187765 Free PMC article.

8

Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly.

Canzio D, Chang EY, Shankar S, Kuchenbecker KM, Simon MD, Madhani HD, Narlikar GJ, Al-Sady B. Canzio D, et al. Among authors: simon md. Mol Cell. 2011 Jan 7;41(1):67-81. doi: 10.1016/j.molcel.2010.12.016. Mol Cell. 2011. PMID: 21211724 Free PMC article.

9

A method to site-specifically incorporate methyl-lysine analogues into recombinant proteins.

Simon MD, Shokat KM. Simon MD, et al. Methods Enzymol. 2012;512:57-69. doi: 10.1016/B978-0-12-391940-3.00003-2. Methods Enzymol. 2012. PMID: 22910202

10

High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation.

Simon MD, Pinter SF, Fang R, Sarma K, Rutenberg-Schoenberg M, Bowman SK, Kesner BA, Maier VK, Kingston RE, Lee JT. Simon MD, et al. Nature. 2013 Dec 19;504(7480):465-469. doi: 10.1038/nature12719. Epub 2013 Oct 27. Nature. 2013. PMID: 24162848 Free PMC article.

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