Holý A - Search Results

1

Mechanism of antiviral drug resistance of vaccinia virus: identification of residues in the viral DNA polymerase conferring differential resistance to antipoxvirus drugs.

Gammon DB, Snoeck R, Fiten P, Krecmerová M, Holý A, De Clercq E, Opdenakker G, Evans DH, Andrei G. Gammon DB, et al. Among authors: holy a. J Virol. 2008 Dec;82(24):12520-34. doi: 10.1128/JVI.01528-08. Epub 2008 Oct 8. J Virol. 2008. PMID: 18842735 Free PMC article.

2

Acyclic nucleoside phosphonates: a key class of antiviral drugs.

De Clercq E, Holý A. De Clercq E, et al. Among authors: holy a. Nat Rev Drug Discov. 2005 Nov;4(11):928-40. doi: 10.1038/nrd1877. Nat Rev Drug Discov. 2005. PMID: 16264436 Review.

3

Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains.

Lebeau I, Andrei G, Krecmerová M, De Clercq E, Holy A, Snoeck R. Lebeau I, et al. Among authors: holy a. Antimicrob Agents Chemother. 2007 Jun;51(6):2268-73. doi: 10.1128/AAC.01422-06. Epub 2007 Apr 9. Antimicrob Agents Chemother. 2007. PMID: 17420214 Free PMC article.

4

Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models.

Duraffour S, Snoeck R, Krecmerová M, van Den Oord J, De Vos R, Holy A, Crance JM, Garin D, De Clercq E, Andrei G. Duraffour S, et al. Among authors: holy a. Antimicrob Agents Chemother. 2007 Dec;51(12):4410-9. doi: 10.1128/AAC.00838-07. Epub 2007 Sep 24. Antimicrob Agents Chemother. 2007. PMID: 17893157 Free PMC article.

5

Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine.

Naesens L, Andrei G, Votruba I, Krecmerová M, Holý A, Neyts J, De Clercq E, Snoeck R. Naesens L, et al. Among authors: holy a. Biochem Pharmacol. 2008 Oct 15;76(8):997-1005. doi: 10.1016/j.bcp.2008.08.009. Epub 2008 Aug 19. Biochem Pharmacol. 2008. PMID: 18773877

6

Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity.

Hocková D, Holý A, Andrei G, Snoeck R, Balzarini J. Hocková D, et al. Among authors: holy a. Bioorg Med Chem. 2011 Aug 1;19(15):4445-53. doi: 10.1016/j.bmc.2011.06.045. Epub 2011 Jun 22. Bioorg Med Chem. 2011. PMID: 21745746 Free PMC article.

7

6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity.

Holý A, Votruba I, Masojídková M, Andrei G, Snoeck R, Naesens L, De Clercq E, Balzarini J. Holý A, et al. J Med Chem. 2002 Apr 25;45(9):1918-29. doi: 10.1021/jm011095y. J Med Chem. 2002. PMID: 11960502

8

5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity.

Hocková D, Holý A, Masojídková M, Andrei G, Snoeck R, De Clercq E, Balzarini J. Hocková D, et al. Among authors: holy a. J Med Chem. 2003 Nov 6;46(23):5064-73. doi: 10.1021/jm030932o. J Med Chem. 2003. PMID: 14584956

9

Antiadenovirus activities of several classes of nucleoside and nucleotide analogues.

Naesens L, Lenaerts L, Andrei G, Snoeck R, Van Beers D, Holy A, Balzarini J, De Clercq E. Naesens L, et al. Among authors: holy a. Antimicrob Agents Chemother. 2005 Mar;49(3):1010-6. doi: 10.1128/AAC.49.3.1010-1016.2005. Antimicrob Agents Chemother. 2005. PMID: 15728896 Free PMC article.

10

Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.

Krecmerová M, Holý A, Pískala A, Masojídková M, Andrei G, Naesens L, Neyts J, Balzarini J, De Clercq E, Snoeck R. Krecmerová M, et al. Among authors: holy a. J Med Chem. 2007 Mar 8;50(5):1069-77. doi: 10.1021/jm061281+. Epub 2007 Feb 14. J Med Chem. 2007. PMID: 17298047

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