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A phase-I trial using a universal GM-CSF-producing and CD40L-expressing bystander cell line (GM.CD40L) in the formulation of autologous tumor cell-based vaccines for cancer patients with stage IV disease.
Dessureault S, Noyes D, Lee D, Dunn M, Janssen W, Cantor A, Sotomayor E, Messina J, Antonia SJ. Dessureault S, et al. Ann Surg Oncol. 2007 Feb;14(2):869-84. doi: 10.1245/s10434-006-9196-4. Epub 2006 Nov 14. Ann Surg Oncol. 2007. PMID: 17103257 Clinical Trial.
Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas.
Lwin T, Hazlehurst LA, Dessureault S, Lai R, Bai W, Sotomayor E, Moscinski LC, Dalton WS, Tao J. Lwin T, et al. Among authors: dessureault s. Blood. 2007 Sep 1;110(5):1631-8. doi: 10.1182/blood-2006-11-060350. Epub 2007 May 14. Blood. 2007. PMID: 17502456 Free PMC article. Clinical Trial.
PRDM1 is required for mantle cell lymphoma response to bortezomib.
Desai S, Maurin M, Smith MA, Bolick SC, Dessureault S, Tao J, Sotomayor E, Wright KL. Desai S, et al. Among authors: dessureault s. Mol Cancer Res. 2010 Jun;8(6):907-18. doi: 10.1158/1541-7786.MCR-10-0131. Epub 2010 Jun 8. Mol Cancer Res. 2010. PMID: 20530581 Free PMC article.
Tumor cell vaccines.
Thompson PL, Dessureault S. Thompson PL, et al. Among authors: dessureault s. Adv Exp Med Biol. 2007;601:345-55. doi: 10.1007/978-0-387-72005-0_37. Adv Exp Med Biol. 2007. PMID: 17713023 Review.
A GM-CSF/CD40L producing cell augments anti-tumor T cell responses.
Dessureault S, Alsarraj M, McCarthy S, Hunter T, Noyes D, Lee D, Harkins J, Seigne J, Jennings R, Antonia SJ. Dessureault S, et al. J Surg Res. 2005 May 15;125(2):173-81. doi: 10.1016/j.jss.2004.11.036. Epub 2005 Jan 28. J Surg Res. 2005. PMID: 15854671
70 results