Pritchard CA - Search Results

1

CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation.

Noble C, Mercer K, Hussain J, Carragher L, Giblett S, Hayward R, Patterson C, Marais R, Pritchard CA. Noble C, et al. Among authors: pritchard ca. Mol Cell. 2008 Sep 26;31(6):862-72. doi: 10.1016/j.molcel.2008.08.026. Mol Cell. 2008. PMID: 18922468 Free PMC article.

2

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.

Heidorn SJ, Milagre C, Whittaker S, Nourry A, Niculescu-Duvas I, Dhomen N, Hussain J, Reis-Filho JS, Springer CJ, Pritchard C, Marais R. Heidorn SJ, et al. Cell. 2010 Jan 22;140(2):209-21. doi: 10.1016/j.cell.2009.12.040. Cell. 2010. PMID: 20141835 Free PMC article.

3

BRAF inactivation drives aneuploidy by deregulating CRAF.

Kamata T, Hussain J, Giblett S, Hayward R, Marais R, Pritchard C. Kamata T, et al. Cancer Res. 2010 Nov 1;70(21):8475-86. doi: 10.1158/0008-5472.CAN-10-0603. Epub 2010 Oct 26. Cancer Res. 2010. PMID: 20978199 Free PMC article.

4

Expression of kinase suppressor of Ras in the normal adult and embryonic mouse.

Giblett SM, Lloyd DJ, Light Y, Marais R, Pritchard CA. Giblett SM, et al. Among authors: pritchard ca. Cell Growth Differ. 2002 Jul;13(7):307-13. Cell Growth Differ. 2002. PMID: 12133899

5

B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts.

Pritchard CA, Hayes L, Wojnowski L, Zimmer A, Marais RM, Norman JC. Pritchard CA, et al. Mol Cell Biol. 2004 Jul;24(13):5937-52. doi: 10.1128/MCB.24.13.5937-5952.2004. Mol Cell Biol. 2004. PMID: 15199148 Free PMC article.

6

V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a.

Carragher LA, Snell KR, Giblett SM, Aldridge VS, Patel B, Cook SJ, Winton DJ, Marais R, Pritchard CA. Carragher LA, et al. Among authors: pritchard ca. EMBO Mol Med. 2010 Nov;2(11):458-71. doi: 10.1002/emmm.201000099. EMBO Mol Med. 2010. PMID: 20941790 Free PMC article.

7

Raf proteins and cancer: B-Raf is identified as a mutational target.

Mercer KE, Pritchard CA. Mercer KE, et al. Among authors: pritchard ca. Biochim Biophys Acta. 2003 Jun 5;1653(1):25-40. doi: 10.1016/s0304-419x(03)00016-7. Biochim Biophys Acta. 2003. PMID: 12781369 Review.

8

ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf.

Mercer K, Chiloeches A, Hüser M, Kiernan M, Marais R, Pritchard C. Mercer K, et al. Oncogene. 2002 Jan 17;21(3):347-55. doi: 10.1038/sj.onc.1205101. Oncogene. 2002. PMID: 11821947

9

A-Raf and Raf-1 work together to influence transient ERK phosphorylation and Gl/S cell cycle progression.

Mercer K, Giblett S, Oakden A, Brown J, Marais R, Pritchard C. Mercer K, et al. Oncogene. 2005 Aug 4;24(33):5207-17. doi: 10.1038/sj.onc.1208707. Oncogene. 2005. PMID: 15856007

10

Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts.

Mercer K, Giblett S, Green S, Lloyd D, DaRocha Dias S, Plumb M, Marais R, Pritchard C. Mercer K, et al. Cancer Res. 2005 Dec 15;65(24):11493-500. doi: 10.1158/0008-5472.CAN-05-2211. Cancer Res. 2005. PMID: 16357158 Free PMC article.

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