McElroy A - Search Results

1

Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents.

Bailey S, Fish PV, Billotte S, Bordner J, Greiling D, James K, McElroy A, Mills JE, Reed C, Webster R. Bailey S, et al. Among authors: mcelroy a. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6562-7. doi: 10.1016/j.bmcl.2008.10.036. Epub 2008 Oct 11. Bioorg Med Chem Lett. 2008. PMID: 18945617

2

Potent and selective nonpeptidic inhibitors of procollagen C-proteinase.

Fish PV, Allan GA, Bailey S, Blagg J, Butt R, Collis MG, Greiling D, James K, Kendall J, McElroy A, McCleverty D, Reed C, Webster R, Whitlock GA. Fish PV, et al. Among authors: mcelroy a. J Med Chem. 2007 Jul 26;50(15):3442-56. doi: 10.1021/jm061010z. Epub 2007 Jun 26. J Med Chem. 2007. PMID: 17591762

3

Design of selective thrombin inhibitors based on the (R)-Phe-Pro-Arg sequence.

Danilewicz JC, Abel SM, Brown AD, Fish PV, Hawkeswood E, Holland SJ, James K, McElroy AB, Overington J, Powling MJ, Rance DJ. Danilewicz JC, et al. J Med Chem. 2002 Jun 6;45(12):2432-53. doi: 10.1021/jm011133d. J Med Chem. 2002. PMID: 12036353

4

Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis.

Bunnage ME, Blagg J, Steele J, Owen DR, Allerton C, McElroy AB, Miller D, Ringer T, Butcher K, Beaumont K, Evans K, Gray AJ, Holland SJ, Feeder N, Moore RS, Brown DG. Bunnage ME, et al. J Med Chem. 2007 Nov 29;50(24):6095-103. doi: 10.1021/jm0702433. Epub 2007 Nov 9. J Med Chem. 2007. PMID: 17990866

5

Conformationally constrained tachykinin analogues: potent and highly selective neurokinin NK-2 receptor agonists.

Deal MJ, Hagan RM, Ireland SJ, Jordan CC, McElroy AB, Porter B, Ross BC, Stephens-Smith M, Ward P. Deal MJ, et al. Among authors: mcelroy ab. J Med Chem. 1992 Oct 30;35(22):4195-204. doi: 10.1021/jm00100a027. J Med Chem. 1992. PMID: 1331460

6

Synthesis of macrocyclic, potential protease inhibitors using a generic scaffold.

Dumez E, Snaith JS, Jackson RF, McElroy AB, Overington J, Wythes MJ, Withka JM, McLellan TJ. Dumez E, et al. J Org Chem. 2002 Jul 12;67(14):4882-92. doi: 10.1021/jo025615o. J Org Chem. 2002. PMID: 12098301

7

New spiropiperidines as potent and selective non-peptide tachykinin NK2 receptor antagonists.

Smith PW, Cooper AW, Bell R, Beresford IJ, Gore PM, McElroy AB, Pritchard JM, Saez V, Taylor NR, Sheldrick RL, et al. Smith PW, et al. Among authors: mcelroy ab. J Med Chem. 1995 Sep 15;38(19):3772-9. doi: 10.1021/jm00019a006. J Med Chem. 1995. PMID: 7562907

8

Highly potent and selective heptapeptide antagonists of the neurokinin NK-2 receptor.

McElroy AB, Clegg SP, Deal MJ, Ewan GB, Hagan RM, Ireland SJ, Jordan CC, Porter B, Ross BC, Ward P, et al. McElroy AB, et al. J Med Chem. 1992 Jul 10;35(14):2582-91. doi: 10.1021/jm00092a008. J Med Chem. 1992. PMID: 1321907

9

Synthesis, antinociceptive activity, and opioid receptor profiles of substituted trans-3-(decahydro- and octahydro-4a-isoquinolinyl)phenols.

Judd DB, Brown DS, Lloyd JE, McElroy AB, Scopes DI, Birch PJ, Hayes AG, Sheehan MJ. Judd DB, et al. Among authors: mcelroy ab. J Med Chem. 1992 Jan;35(1):48-56. doi: 10.1021/jm00079a005. J Med Chem. 1992. PMID: 1310115

10

Matrix metalloproteinase inhibitors containing a (carboxyalkyl)amino zinc ligand: modification of the P1 and P2' residues.

Brown FK, Brown PJ, Bickett DM, Chambers CL, Davies HG, Deaton DN, Drewry D, Foley M, McElroy AB, Gregson M, et al. Brown FK, et al. Among authors: mcelroy ab. J Med Chem. 1994 Mar 4;37(5):674-88. doi: 10.1021/jm00031a018. J Med Chem. 1994. PMID: 8126708

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