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Wnt/beta-catenin signaling controls development of the blood-brain barrier.
Liebner S, Corada M, Bangsow T, Babbage J, Taddei A, Czupalla CJ, Reis M, Felici A, Wolburg H, Fruttiger M, Taketo MM, von Melchner H, Plate KH, Gerhardt H, Dejana E. Liebner S, et al. Among authors: von melchner h. J Cell Biol. 2008 Nov 3;183(3):409-17. doi: 10.1083/jcb.200806024. Epub 2008 Oct 27. J Cell Biol. 2008. PMID: 18955553 Free PMC article.
Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer.
Sterner-Kock A, Thorey IS, Koli K, Wempe F, Otte J, Bangsow T, Kuhlmeier K, Kirchner T, Jin S, Keski-Oja J, von Melchner H. Sterner-Kock A, et al. Among authors: von melchner h. Genes Dev. 2002 Sep 1;16(17):2264-73. doi: 10.1101/gad.229102. Genes Dev. 2002. PMID: 12208849 Free PMC article.
Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.
Heidler J, Fysikopoulos A, Wempe F, Seimetz M, Bangsow T, Tomasovic A, Veit F, Scheibe S, Pichl A, Weisel F, Lloyd KC, Jaksch P, Klepetko W, Weissmann N, von Melchner H. Heidler J, et al. Among authors: von melchner h. Dis Model Mech. 2013 Nov;6(6):1378-87. doi: 10.1242/dmm.013482. Epub 2013 Aug 29. Dis Model Mech. 2013. PMID: 24046361 Free PMC article.
TGF-beta activation by traction?
Keski-Oja J, Koli K, von Melchner H. Keski-Oja J, et al. Among authors: von melchner h. Trends Cell Biol. 2004 Dec;14(12):657-9. doi: 10.1016/j.tcb.2004.10.003. Trends Cell Biol. 2004. PMID: 15564041 Review.
Gene-trap vectors and mutagenesis.
De-Zolt S, Altschmied J, Ruiz P, von Melchner H, Schnütgen F. De-Zolt S, et al. Among authors: von melchner h. Methods Mol Biol. 2009;530:29-47. doi: 10.1007/978-1-59745-471-1_3. Methods Mol Biol. 2009. PMID: 19266330
86 results