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Page 1
Dihydropyrrole[2,3-d]pyridine derivatives as novel corticotropin-releasing factor-1 antagonists: mapping of the receptor binding pocket by in silico docking studies.
Di Fabio R, Arban R, Bernasconi G, Braggio S, Blaney FE, Capelli AM, Castiglioni E, Donati D, Fazzolari E, Ratti E, Feriani A, Contini S, Gentile G, Ghirlanda D, Sabbatini FM, Andreotti D, Spada S, Marchioro C, Worby A, St-Denis Y. Di Fabio R, et al. Among authors: ghirlanda d. J Med Chem. 2008 Nov 27;51(22):7273-86. doi: 10.1021/jm800743q. J Med Chem. 2008. PMID: 18975927
Synthesis and SAR of substituted tetrahydrocarbazole derivatives as new NPY-1 antagonists.
Di Fabio R, Giovannini R, Bertani B, Borriello M, Bozzoli A, Donati D, Falchi A, Ghirlanda D, Leslie CP, Pecunioso A, Rumboldt G, Spada S. Di Fabio R, et al. Among authors: ghirlanda d. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1749-52. doi: 10.1016/j.bmcl.2005.11.104. Epub 2005 Dec 20. Bioorg Med Chem Lett. 2006. PMID: 16364642
Novel carbazole derivatives as NPY Y1 antagonists.
Leslie CP, Di Fabio R, Bonetti F, Borriello M, Braggio S, Dal Forno G, Donati D, Falchi A, Ghirlanda D, Giovannini R, Pavone F, Pecunioso A, Pentassuglia G, Pizzi DA, Rumboldt G, Stasi L. Leslie CP, et al. Among authors: ghirlanda d. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1043-6. doi: 10.1016/j.bmcl.2006.11.034. Epub 2006 Nov 16. Bioorg Med Chem Lett. 2007. PMID: 17127055
Synthesis and pharmacological characterization of novel druglike corticotropin-releasing factor 1 antagonists.
Di Fabio R, St-Denis Y, Sabbatini FM, Andreotti D, Arban R, Bernasconi G, Braggio S, Blaney FE, Capelli AM, Castiglioni E, Di Modugno E, Donati D, Fazzolari E, Ratti E, Feriani A, Contini S, Gentile G, Ghirlanda D, Provera S, Marchioro C, Roberts KL, Mingardi A, Mattioli M, Nalin A, Pavone F, Spada S, Trist DG, Worby A. Di Fabio R, et al. Among authors: ghirlanda d. J Med Chem. 2008 Dec 11;51(23):7370-9. doi: 10.1021/jm800744m. J Med Chem. 2008. PMID: 18989952
Substituted tetraazaacenaphthylenes as potent CRF1 receptor antagonists for the treatment of depression and anxiety.
St-Denis Y, Di Fabio R, Bernasconi G, Castiglioni E, Contini S, Donati D, Fazzolari E, Gentile G, Ghirlanda D, Marchionni C, Messina F, Micheli F, Pavone F, Pasquarello A, Sabbatini FM, Zampori MG, Arban R, Vitulli G. St-Denis Y, et al. Among authors: ghirlanda d. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3713-6. doi: 10.1016/j.bmcl.2005.05.040. Bioorg Med Chem Lett. 2005. PMID: 15946843