Georg GI - Search Results

1

Synthesis, tubulin assembly, and antiproliferative activity against MCF7 and NCI/ADR-RES cancer cells of 10-O-acetyl-5'-hydroxybutitaxel.

Ge H, Wang J, Kayser MM, Himes RH, Georg GI. Ge H, et al. Among authors: georg gi. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6165-7. doi: 10.1016/j.bmcl.2008.10.010. Epub 2008 Oct 7. Bioorg Med Chem Lett. 2008. PMID: 18977659 Free PMC article.

2

Synthesis of biologically active taxol analogues with modified phenylisoserine side chains.

Georg GI, Cheruvallath ZS, Himes RH, Mejillano MR, Burke CT. Georg GI, et al. J Med Chem. 1992 Oct 30;35(22):4230-7. doi: 10.1021/jm00100a031. J Med Chem. 1992. PMID: 1359143

3

Interaction of a fluorescent paclitaxel analogue with tubulin.

Sengupta S, Boge TC, Georg GI, Himes RH. Sengupta S, et al. Among authors: georg gi. Biochemistry. 1995 Sep 19;34(37):11889-94. doi: 10.1021/bi00037a029. Biochemistry. 1995. PMID: 7547924

4

Novel cytotoxic 3'-(tert-butyl) 3'-dephenyl analogs of paclitaxel and docetaxel.

Ali SM, Hoemann MZ, Aubé J, Mitscher LA, Georg GI, McCall R, Jayasinghe LR. Ali SM, et al. Among authors: georg gi. J Med Chem. 1995 Sep 15;38(19):3821-8. doi: 10.1021/jm00019a012. J Med Chem. 1995. PMID: 7562913

5

Synthesis of a photoaffinity taxol analogue and its use in labeling tubulin.

Dasgupta D, Park H, Harriman GC, Georg GI, Himes RH. Dasgupta D, et al. Among authors: georg gi. J Med Chem. 1994 Sep 2;37(18):2976-80. doi: 10.1021/jm00044a019. J Med Chem. 1994. PMID: 7915327

6

Structure-activity studies of antitumor taxanes: synthesis of novel C-13 side chain homologated taxol and taxotere analogs.

Jayasinghe LR, Datta A, Ali SM, Zygmunt J, Vander Velde DG, Georg GI. Jayasinghe LR, et al. Among authors: georg gi. J Med Chem. 1994 Sep 2;37(18):2981-4. doi: 10.1021/jm00044a020. J Med Chem. 1994. PMID: 7915328

7

The effect of the aromatic rings of taxol on biological activity and solution conformation: synthesis and evaluation of saturated taxol and taxotere analogues.

Boge TC, Himes RH, Vander Velde DG, Georg GI. Boge TC, et al. Among authors: georg gi. J Med Chem. 1994 Sep 30;37(20):3337-43. doi: 10.1021/jm00046a018. J Med Chem. 1994. PMID: 7932561

8

4-Deacetyltaxol and 10-acetyl-4-deacetyltaxotere: synthesis and biological evaluation.

Datta A, Jayasinghe LR, Georg GI. Datta A, et al. Among authors: georg gi. J Med Chem. 1994 Nov 25;37(24):4258-60. doi: 10.1021/jm00050a023. J Med Chem. 1994. PMID: 7990125

9

Interaction of cryptophycin 1 with tubulin and microtubules.

Kerksiek K, Mejillano MR, Schwartz RE, Georg GI, Himes RH. Kerksiek K, et al. Among authors: georg gi. FEBS Lett. 1995 Dec 11;377(1):59-61. doi: 10.1016/0014-5793(95)01271-0. FEBS Lett. 1995. PMID: 8543019 Free article.

10

Preparation of phenolic paclitaxel metabolites.

Park H, Hepperle M, Boge TC, Himes RH, Georg GI. Park H, et al. Among authors: georg gi. J Med Chem. 1996 Jul 5;39(14):2705-9. doi: 10.1021/jm960142x. J Med Chem. 1996. PMID: 8709100

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